Cyclosporine
CYP3A immuno-suppressant. Stops T-cells from growing
Felodipine
CYP3A Calcium-channel blocker
Grapefruit juice
CYP3A inhibitor
Ketoconazole
CYP3A inhibitor, Azole antifungal agent
Rifampin
CYP3A Inducer, a Rifamycin
Amitriptyline
CYP2D6 tricyclic antidepressant
Clomipramine
CYP2D6 tricyclic antidepressant
Desipramine
CYP2D6 tricyclic antidepressant
Imipramine
CYP2D6 tricyclic antidepressant
Nortryptyline
CYP2D6 tricyclic antidepressant
Codeine
CYP2D6 opioid, can be converted to morphine
Quinidine
CYP2D6 Inhibitor
CYP2D6
CYP sub-family that usually activates drugs
Fluoxetine
CYP2D6 inhibitor
Paroxetine
CYP2D6 inhibitor
Warfarin
aka Coumadin, CYP2C19 substrate, anti-coagulant. Inhibits VKORC1 from reducing Vit K
Isoniazid
N-acetyltransferase (NAT) enzyme, used to treat TB
6-mercaptopurine
Destabilizes thiopurine methyltransferase (TMPT) to treat ALL (leukemia) or IBD
6-thioguanine
Destabilizes thiopurine methyltransferase (TMPT) to treat ALL (leukemia) or IBD
Sulfonamide
treats G6PD deficient patients
Dapsone
treats G6PD deficient patients
Azanthioprine
Thioprine methytransferase inhibitor, ALL (leukemia) cure by myelosuppression
Imiglucerase
aka Cerazyme. Gaucher disease drug that is β-glucocerebrosidase analog
Velaglucerase (VPRIV)
Gaucher disease drug that is hydrolytic lysosomal glucocerebrosidase
Taliglucerase alfa
Gaucher disease drug that is hydrolytic lysosomal glucocerebrosidase from carrots
Miglustat
aka Zavesca Gaucher disease drug that inhibits glucosylceramide synthase (substrate reduct. therapy)
Gleevec
tyrosine kinase inhibitor to treat CML (leukemia)
