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Flashcards in Drugs Deck (40)
1

Olanzapine SE

Avoid in DM and obese = weight gain & sedation

2

Risperidone SE

More movement disorders

3

Quetiapine SE

LESS movement disorders

4

Ziprasidone SE

Prolonged QT - avoid w/ conduction defects

5

Clozapine SE

Agranulocytosis = CBC

6

Antipsychotic w/ LEAST weight gain

Aripipazole

7

DOC for trigeminal neuralgia

Carbemazepine --> check CBC

8

DOC for dog and human bite wounds

Augmentin
- PCN allergy = cipro and clinda

9

DOC for chloroquine resistant malaria

Mefloquine (pregnancy) > doxy or atovaquone

10

Malaria drug w/ prominent hemolysis in G6PD deficiency

Chloroquine - only w/o Falciparum in places like Korea

11

HIV drug side effects
1. Kidney stones
2. Pancreatitis
3. Hypersensitivity
4. Lactic acidosis
5. Steven-Johnson
6. Liver failure

1. Indinavir - protease inhibitor
2. Didanosine
3. Abacavir
4. NRTIs
5. NNRTIs
6. Nevirapine

12

Drug for both depression and nicotine addiction and its SE

Bupropion --> SEIZURE

13

Mech for niacin-induced flushing

PG induced vasodilation - aspirin prevents

14

Drug assoc w/ red/orange body fluids

Rifampin

15

Hypothermia inducing psych med

Fluphenazine - inhibits shivering

16

Tx Chancroid

Single 1g PO Azithromycin

17

Isotretinoin SE

*Teratogen
*Suicide
HLD, LFTs

18

Drugs that cause hyperK

BBs
ACE
K+ sparing diuretics - ENaC
Digitalis - Na/K+ pump
Cyclosporine, heparin - block aldo
NSAIDs - dec renal pefusion
Succ - leakage
TMP - blocks Na channel in CD, artificial inc in Cr (GFR same)

19

Drugs that cause cholestasis

Ceftriaxone
Azithro

20

Drug to tx cat-scratch

Azithromycin

21

CI to metformin

Cr >1.5 men --> RF & lactic acidosis

22

DM med SE = weight gain and hypoglycemia

Sulfonylureas (glipizide)

23

DM med SE = CHF, bladder cancer, fx

TZDs (pioglitazone)

24

DM med if weight loss desired

GLP-1 agonist (exanitide)
- acute pancreatitis

25

HbA1c level to add insulin to metformin

>8.5

26

SE of amiodarone

Pulmonary
Hypothyroid > hyper
LFTs
Corneal deposits - no need to stop drug
Blue-gray skin on face

27

Plan B drug

levonorgestrel - up to 120hrs

28

Cyclosorine mech & SE

Inhibits IL-2

Gingival hypertrophy
SCC
Hyperglycemia
Tremor, akinetic mutism
HTN
Nephrotoxic --> gout, hyperK

29

Azathioprine mech & SE

Inhibits purine synthesis

Diarrhea
Leukopenia
Hepatotoxicity

30

Mycophenolate mech & SE

Inhibits IMPDH in purine synthesis

MARROW suppression

31

Tamoxifen SE

ENDOMETRIAL CA
DVT

32

Tx for enterobius

Albendazole

33

Risk w/ lidocaine w/ ACS

Inc ASYSTOLE

34

Tx of Legionella

Levo
Azithro

35

Gram + partially acid-fast branching rods tx?

Nocardia = TMP-SMX

36

Tx mucormycosis

Debridement + IV amphotericin B

37

Efavirenz SE

Insomnia, bizarre dreams

38

Tx severe hypertriglyceridemia or xanthomas

Fibrates

39

Mech of glipizide (sulfonylurea)

Inc endogenous insulin production

40

Prolongs QT

Procainamide
Amiodarone
Sotaolol
Propenafone