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ESA 2- Membranes and Receptors > Drugs > Flashcards

Flashcards in Drugs Deck (30):
1

Give an example of a nicotinic cholinoceptor antagonist?

Tubocararine

2

What is the action of tubocurarine?

Muscle paralysis during anasthesia

3

Give 4 examples of muscarinic cholinoceptor antagonists

HyoscineIpratropium bromideHomatropine Tropicamide

4

What is hyoscine used for?

Anaesthetic premedication

5

What is ipratropium bromide used for?

Treat bronchoconstriction in asthmatics

6

What is homatropine and tropicamide used for?

Pupillary dilation and paralysis

7

Give an example of a muscarinic cholinoreceptor agonist?

Pilocarpine

8

What is pilocarpine used for?

Treatment of glaucoma Increased GI motility after surgerySuppression of atrial tachycardia Stimulates bladder emptying

9

Give 5 examples of cholinesterase inhibitors

Edrophonium Physostigimine Dyflos TacrineDonepezil

10

What is edrophonium, physostigimine, and dyflos used for?

Treatment of glaucomaMyasthenia gravis

11

What is tacrine and donepezil used for?

Treatment of Alzheimer's disease

12

Give an example of a selective ß1 agonist

Dobutamine

13

What does dobutamine do?

#NAME?

14

Give an example of a selective ß2 agonist

Salbutamol

15

What does salbutamol do?

Bronchodilation

16

Give two examples of a selective α1 agonist?

Phenylephrine Adrenaline

17

What is phenylephrine used for?

Nasal decongestants

18

What is adrenaline used for?

Local vasoconstriction to retard the dissipation of anaesthetic

19

Give an example of a selective α2 agonist

Clonidine

20

What is clonidine used for?

Anti-hypertension

21

What does clonidine do?

Acts on presynaptic receptors to reduce NA release

22

Give an example of a α-antagonist

Phentolamine

23

What does phentolamine do?

Peripheral vasodilation

24

What is phentolamine used for?

To treat peripheral vascular disease

25

Why is phentolamine not used to treat hypertension?

It can cause postural hypotension

26

Give an example of a selective α1 antagonist

Prazosin

27

What is prazosin used for?

Treat hypertension

28

Give an example of a ß-antagonist (blocker)

Propanolol

29

What is propanolol used for?

Treat hypertension, MI, angina

30

What are the unwanted side effects of propanolol?

Bronchoconstriction