Drugs Flashcards

(30 cards)

1
Q

examples of anti-cholesterol drugs

A

statins, fibrates, PCSK 9 inhibitors

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2
Q

examples of anti-hypertensive drugs

A

thiazide diuretics, beta blockers, vasodilators

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3
Q

examples of statins

A

simvastatin, atorvastatin

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4
Q

examples of PCSK 9 inhibitors

A

evolocumab, alirocumab

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5
Q

examples of vasodilators

A

calcium antagonists, alpha blockers, ACEI, ARB

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6
Q

statin example

A

simvastatin

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7
Q

what do statins do

A

blocks HMG CoA reductase

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8
Q

what are statins used in

A

hypercholesterolaemia, diabetes, angina/MI, CVA/TIA, high risk of MI and CVA

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9
Q

what are the side effects pf statins

A

myopathy, rhabdomyolysis (renal failure)

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10
Q

example of fibrates

A

bexafibrate

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11
Q

what are fibrates used in

A

hypertriglyceridaemia, low HDL cholesterol

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12
Q

what do PCSK 9 inhibitors do

A

inhibits binding of PCSK9 binding to LDLR, increasing number of LDLRs free to clear LDL (lowering levels)

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13
Q

examples of antihypertension drugs

A

thiazide diuretics, beta-blockers, vasodilators mineral corticoid antagonist

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14
Q

examples of vasodilators

A

calcium antagonists, alpha blockers, ACE inhibitors, ARB

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15
Q

ACEI

A

ACE inhibitors

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16
Q

ARB

A

angiotensin receptor blockers

17
Q

example of mineral corticoid antagonists

A

spironolactone

18
Q

example of thiazide diuretics

A

bendrofluazide

19
Q

what is bendrofluazide used for

20
Q

example of loop diuretics

21
Q

what is furosemide used for

A

heart failure

22
Q

what are side effects of diuretics

A

hypokalaemia, arrhythmias, hyperglycaemia, increased uric acid, impotence

23
Q

examples of cardio-selective beta-blockers

A

atenolol, bisoprolol

24
Q

cardio-selective beta-blockers block what receptor

25
what are cardio-selective beta-blockers used for
angina, acute coronary syndrome, MI, hypertension, heart failure
26
examples of non-selective beat blockers
propranolol, carvedilol
27
carvedilol is an _ beta blocker
alpha and beta
28
non-selective beta-blockers block what receptors
beta 1 and 2
29
what are non-selective beta blockers used for
thyrotoxicosis, migrane
30
side effects of non-selective beta blockers
asthma, tired, heart failure, cold peripheries