Drugs Flashcards
(30 cards)
examples of anti-cholesterol drugs
statins, fibrates, PCSK 9 inhibitors
examples of anti-hypertensive drugs
thiazide diuretics, beta blockers, vasodilators
examples of statins
simvastatin, atorvastatin
examples of PCSK 9 inhibitors
evolocumab, alirocumab
examples of vasodilators
calcium antagonists, alpha blockers, ACEI, ARB
statin example
simvastatin
what do statins do
blocks HMG CoA reductase
what are statins used in
hypercholesterolaemia, diabetes, angina/MI, CVA/TIA, high risk of MI and CVA
what are the side effects pf statins
myopathy, rhabdomyolysis (renal failure)
example of fibrates
bexafibrate
what are fibrates used in
hypertriglyceridaemia, low HDL cholesterol
what do PCSK 9 inhibitors do
inhibits binding of PCSK9 binding to LDLR, increasing number of LDLRs free to clear LDL (lowering levels)
examples of antihypertension drugs
thiazide diuretics, beta-blockers, vasodilators mineral corticoid antagonist
examples of vasodilators
calcium antagonists, alpha blockers, ACE inhibitors, ARB
ACEI
ACE inhibitors
ARB
angiotensin receptor blockers
example of mineral corticoid antagonists
spironolactone
example of thiazide diuretics
bendrofluazide
what is bendrofluazide used for
hypertension
example of loop diuretics
furosemide
what is furosemide used for
heart failure
what are side effects of diuretics
hypokalaemia, arrhythmias, hyperglycaemia, increased uric acid, impotence
examples of cardio-selective beta-blockers
atenolol, bisoprolol
cardio-selective beta-blockers block what receptor
beta 1