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Flashcards in Drugs and Mental Health Deck (25):
0

What is psychopharmacology?

The science of drug treatment of psychiatric disorders

1

What drugs are used to treat a) depression, b) schizophrenia and b) anxiety?

a) antidepressants
b) antiphyschotics
c) anxiolytics

2

What is covered in the term anxiety?

Panic disorder, OCD, generalised anxiety disorder, social anxiety disorder, phobias.

3

What are the physiological effects of anxiety?

Sweating, sleep disorder and tense muscles

4

What are the physchological effects of anxiety?

Feeling worried, nervous and agitated

5

What are the most important anxiolytics?

Benzodiazepines

6

What do benzodiazepines selectively act on?

GABAa receptors, enhance GABA response by opening GABA-activated cl- channels

7

What are the effects of benzodiazepines?

Reduced anxiety, sedation, reduced muscle tone and coordination and anticonvulsant.

8

What are the unwanted effects of benzodiazepines?

Drowsiness, confusion, loss of coordination, amnesia, tolerance and dependence

9

What are you most likely to suffer with depression?

A weakened immune system

10

What is depression often termed?

MDD

11

What are the symptoms of depression?

Sad/depressed mood, loss of pleasure, disruption of appetite, sleep and concentration, loss of energy, fatigue, negative self-concept and reluctant thoughts of death

12

What is the hypotheses which states that depression is due to low levels of amine in the brain?

Biogenic amine hypothesis

13

What are the three types of drugs used to treat depression ?

SSRIs, TCAs and MAOII

14

Give an examples of a SSRIs?

Proxitine, sertraline and Prozac

15

What is the big problem with antidepressants

They have a delay of at least 2 weeks

16

What are the unwanted effects of SSRIs?

Nausea, anorexia, insomnia, aggression/violence and sexual dysfunction

17

Why are SSRIs better than TCAs or MAOIIs?

They cannot kill you, they are no more effective

18

What are the three types of symptoms of schizophrenia?

Positive (aka type 1): visual/auditory hallucinations
Negative (aka type 2): apathy, lack of emotion, poor or non-existent social functioning
Cognitive symptoms: loss of concentration, memory and lack of ability to follow rules

19

What symptoms of schizophrenia occur when?

Positive usually earlier on when younger and then negative and cognitive with time and age.

20

What is the hypothesis of the cause of schizophrenia?

Dopamine hypothesis

21

What is the dopamine hypothesis?

Poor regulation of dopamine transmission.

22

What are clinically used antiphyschotics?

Dopamine antagonists

23

What two groups do antiphyschotics split into?

Typical and a typical

24

What are the unwanted effects of antiphyschotics?

Extra pyramidal syndrome, they block muscarinic receptors which leads to a dry mouth and blurred vision