Drugs B15 Flashcards Preview

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Flashcards in Drugs B15 Deck (21)
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1
Q

Albuterol

A

USE: DOC for prompt asthma attack
MOA: SABA, stabilizes mast cell membranes
SE: Skeletal muscle tremor and cardiac stimulation

2
Q

Salmeterol

A

USE: Adjunctive therapy
MOA: LABA
SE: Skeletal muscle tremor and cardiac stimulation

3
Q

Fluticasone

A

USE:
1. inhibit inflammation
2. decrease mucous production and hypesecretion
3. Increase B2 receptor levels
MOA: Act on cytoplasmic glucocorticoid receptors to stimulate protein synthesis
SE: THRUSH (with inhaled form)

4
Q

Tiotropium (“trops” like atropine)

A

USE: COPD
MOA: LAMA (long acting muscarinic antagonist)

5
Q

Cromolyn

A

USE: Anti-inflamatory
MOA: Inhibit pulmonary mast cell degranulation

6
Q

Montelukast

A

USE: Leukotriene Antagonist
MOA: Blocking Leukotriene receptor- Cys-LT1
SE: Headache

7
Q

Zileuton

A

USE: Leukotriene antagonist, alternative to inhaled steroids, children, orally, allergies
MOA: Blocks 5-lipoxgenase enzyme (synthesis)

8
Q

Bupropion (zyban)

A

USE: Smoking cessation, anti-depressant
MOA: Blocks NE and Dopamine reuptake
SE: suicide

9
Q

Varenciline (chantix)

A

USE: Smoking Cessation
MOA: Nicotinic receptor partial agonist
SE: suicide

10
Q

What is the top strategy for COPD?

A

Bronchodilators: SABA (as needed) and LAMA (daily prevention)

11
Q

Phenylephrine

A

USE: Acute and chronic Rhinitis (decongestant, decrease mucus production)
MOA: Stimulate alpha 1 receptors

12
Q

Dextromethorphan

A

USE: Cough
MOA:
SE: CNS depression

13
Q

Benzonatate

A

Cough suppressants

14
Q

Guaifenesin

A

Expectorant that decreases adhesiveness and surface tension

15
Q

Mesalamine

A

USE: Crohn’s Disease!
MOA: Works anywhere throughout GI tract

16
Q

Sulfasalazine

A

USE: ONLY Ulcerative Colitis!
MOA: broken down in colon so only acitve after the colon (and Crohn’s could be before that)

17
Q

Infliximab, Natalizumab

A

Anti-TNF alpha drugs
Natalizumab= alpha 4-integrin
-blocks leukocyte migration to sites of inflammation

18
Q

Ondansetron (“setrons”)

A

5HT3 receptor blocker

dance you take a 5H3T

19
Q

Promethazine

A

D2 receptor blocker

Hes pretty much a Pro, he went D2

20
Q

Diphenhydramine

A

1st gen H1 blocker

21
Q

Aprepitant

A

Cancer Chemotherapy pts
NK1 antagonist
Substance P