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Baloney > Drugs - Cancer > Flashcards

Drugs - Cancer Flashcards

1
Q

Drug for ER+ (Estrogen Receptor positive) breast cancer in pre and post menopausal women?

A

Tamoxifen - SERM

Prevention of BrCa in high risk women

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2
Q

Dosage of Tamoxifen?

A

Oral daily for 5 years

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3
Q

Safer alternative to Tamoxifen?

A

Raloxifene - SERM

Equally effective - lower incidence uterine cancer and blood clots

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4
Q

Drug for HER2 Receptor positive breast cancer?

A

Trastuzumab

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5
Q

Drug for HER2 Receptor positive breast cancer?

A

Trastuzumab

Monoclonal antibody

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6
Q

Cancers treatable with 5-Fluorouracil?

A

Orally -> Colon, rectal, stomach, pancreas, breast cancer

Topically -> Superficial basal cell carcinoma

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7
Q

Two drugs for Ovarian Cancer?

A

Paclitaxel

Doxorubicin

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8
Q

Cancers treatable with 5-Fluorouracil?

A

Orally -> Colon, rectal, stomach, pancreas, breast cancer
Topically -> Superficial basal cell carcinoma

Anti-metabolite - S phase

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9
Q

Paclitaxel is a second line drug for?

A

Metastatic ovarian or breast cancer - if unresponsive to first line drugs

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10
Q

Drug for Hodgkin’s Lymphoma?

A

Vinblastine

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11
Q

Drug for Non-Small Cell Lung Cancer?

A

Paclitaxel

Mitotic inhibitor

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12
Q

Drug for Lymphocytic lymphoma?

A

Vinblastine

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13
Q

Drug for Kaposi’s Sarcoma?

A

Vinblastine

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14
Q

Drug for Hodgkin’s Lymphoma?

A

Vinblastine

Mitotic inhibitor

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15
Q

Drug for Testicular cancer?

A

Vinblastine

Mitotic inhibitor

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16
Q

Drug for Lymphocytic lymphoma?

A

Vinblastine

Mitotic inhibitor

17
Q

Drug for Kaposi’s Sarcoma?

A

Vinblastine

Mitotic inhibitor

18
Q

Drug for AIDS related Kaposi’s Sarcoma?

A

Doxorubicin

Anthracycline

19
Q

Drug for metastatic breast cancer?

A

Doxorubicin

Anthracycline

20
Q

Cancers treatable with Vinblastine?

A

Hodgkin’s Lympoma
Testicular Cancer
Lymphocytic lymphoma
Kaposi’s sarcoma

21
Q

Cancers treatable with Methotrexate (Anti-metabolite)?

A

Choriocarcinoma and other trophoblastic tumors
Leukemias
Breast, head, lung, neck cancers

22
Q

Other conditions treated with methotrexate?

A

Severe psoriasis
Rheumatoid arthritis
Mycosis fungoides

23
Q

Drug for Leukemia?

A

Methotrexate

24
Q

Drug for Choriocarcinoma?

A

Methotrexate

25
Q

Drug for preventing post menopausal osteoporosis?

A

Raloxifene - SERM

26
Q

Drug for advanced or locally advanced breast cancer?

A

Anastrozole - Aromatase P450 Inhibitor

Baloney (37 decks)

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