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Pre-reg Exam 2021 > Drugs, Driving, Side effects > Flashcards

Drugs, Driving, Side effects Flashcards

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1
Q

What are the drugs with driving warnings?

A

Sedating drugs, effects increased by alcohol

Antihistamines
Antiepileptic 
Antipsychotics 
Opioids
TCA
Baclofen
Hypnotics 
Benzodiazepines 
Quinolones
Selegiline 
Apomorphine
Levodopa
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2
Q

What drugs cause hypotension?

A

Alpha blockers

Dopamine receptor agonists

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3
Q

What drugs cause hypoglycaemia?

A

Sulphonylureas

Insulin

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4
Q

What is an adverse drug reaction?

A

Unwanted or harmful reaction experienced following the administration of a drug, combination of drugs under normal conditions of use which is suspected to be relayed to the drug

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5
Q

When do you report adverse drug reactions?

A

Newer drugs and vaccines
Medication errors
Medical devices
Defective medicine or suspected fake medicines

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6
Q

What drugs cause oral ulcers?

A 
ACEi
NSAID
Nicorandil
Pancreatin
Cytotoxic
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7
Q

What drugs cause oral candidiasis?

A

Corticosteroid inhalers

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8
Q

What drugs cause staining of teeth?

A

Chlorhexidine (brown)

Liquid iron (black)

Tetracyclines (yellow + grey)

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9
Q

What drugs cause osteonecrosis of the jaw?

A

Bisphosphonates

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10
Q

What drugs cause gingival hypertrophy?

A

Ciclosporin
Nifedipine
Phenytoin

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11
Q

What drugs cause dry mouth?

A 
Antimuscarinics 
Antipsychotics 
Opioids
Excessive diuretics
Antihistamines
Antidepressants
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12
Q

What drugs cause taste disturbance?

A 
ACEi
Amiodarone
Carbimazole 
Clarithromycin 
Lithium 
Metformin
Metronidazole 
Zopiclone
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13
Q

What are the drugs that cause myelosuppression?

A

DMARDs - methotrexate, penicillamine, gold

Antiepileptics - carbamazepine, ethosuximide, lamotrigine, phenytoin

Antibiotics- linezolid, chloramphenicol, dapsone, co-trimoxazole, trimethoprim

Immunosuppressants- azathioprine, cytotoxics

Antifolates - phenytoin, methotrexate, trimethoprim

Others - aminosalicylates, carbimazole, clozapine, mirtazapine

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14
Q

What are the symptoms of myelosuppression?

A

Low blood count

Susceptible to infection
Anaemia
Thrombocytopenia

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15
Q

What are the drugs that cause photo sensitisation?

A

Antifungals - voriconazole
Tetracyclines- doxycycline, demeclocycline
Co-trimoxazole, quinolones (oxacins)
Hydroxychloroquine, chloroquine

Amiodarone
PhenothiazineS
Tacrolimus
Topical NSAIDs
Benzoyl peroxide 
Isotretinoin 
Vitamin A
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16
Q

What drugs cause contact sensitisation?

A

Methotrexate
Chlorpromazine
Cytotoxics

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17
Q

What drugs cause QT prolongation?

A

Antipsychotics- pimozide, haloperidol, quetiapine
Antidepressants- citalopram/escitalopram, TCA, venlafaxine
Anti-arrhythmics - sotalol, amiodarone
CNS - methadone, lithium, triptans, apomorphine, ondansetron, domperidone, metoclopramide, quinine

Macrolides, hydroxychloroquine, chloroquine, quinolone, ketoconazole, itraconazole

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18
Q

What are the predisposing factors for QT prolongation?

A 
Increasing age
Female
Cardiac disease
Bradycardia 
Electrolyte disturbances
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19
Q

What are the drugs that cause hypokalaemia?

A 
Loop/thiazide diuretics
Corticosteroids 
Beta 2 agonist
Theophylline 
Stimulant laxatives
Amphotericin B
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20
Q

What are the drugs that increase the risk of bleeding?

A

Anti platelets - NSAID, SSRI, venlafaxine, clopidogrel, prasugrel, glycoprotein inhibitors (abciximab)

Anticoagulants - warfarin, heparins, heparinoids, DOACs, fibrinolytics

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21
Q

What are the drugs that cause thromboembolism?

A

Cytotoxics - bleomycin, cyclophosphamide, thalidomide, vinca alkaloids, tamoxifen

Epoietin Alfa, oestrogens, tranexamic acid

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22
Q

What are the drugs that cause bradycardia?

A 
Beta blockers
Amiodarone
Digoxin 
Rate limiting CCBs
Clonidine
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23
Q

What drugs cause first dose hypotension?

A

Alpha blockers
ACEi/ARB
Nitrates
Indoramin

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24
Q

What drugs cause hypotension?

Study These Flashcards
A

Beta blockers
CCBs
ACEi/ARB
Alpha blockers

Alcohol, dopamine receptor agonists, nitrates, diuretics, sildenafil, gliflozins, antipsychotics

25
What are the drugs that cause antimuscarinic effects?
``` Antimuscarinics Atropine TCA Antihistamines Clozapine Antipsychotics ```
26
What are the drugs cause CNS depressant effects?
``` Alcohol Agomelatine Anaesthetics Antiepileptics Antihistamines Antipsychotics Baclofen Benzodiazepines Ketamine Melatonin Opioids Venlafaxine Z drugs ```
27
What are the drugs that cause peripheral neuropathy?
``` Amiodarone Cisplatin Disulfiram Phenytoin Isoniazid Metronidazole Vinka alkaloids ```
28
What are the drugs causing serotonin syndrome?
Triptans, bupropion, buspirone, TCA, MAOI, SSRI, MAOB inhibitors (selegiline), 5HT3 antagonist (ondansetron), amfetamines, St. John’s wort
29
What are the drugs that cause ototoxicity?
``` Aminoglycosides Cisplatin Glycopeptides (vancomycin) Loop diuretics Vinca alkaloids ```
30
What are the drugs that lower the seizure threshold?
``` Quinolones Mefloquine SSRI Antipsychotics Tramadol Theophylline Lithium Baclofen Amfetamines ```
31
What drugs cause oral ulcers?
``` ACEi NSAID Nicorandil Pancreatin Cytotoxic ```
32
What drugs cause oral candidiasis?
Corticosteroid inhalers
33
What drugs cause staining of teeth?
Chlorhexidine (brown) Liquid iron (black) Tetracyclines (yellow + grey)
34
What are the drugs that lower the seizure threshold?
``` Quinolones Mefloquine SSRI Antipsychotics Tramadol Theophylline Lithium Baclofen Amfetamines ```
35
What are the drugs that cause ototoxicity?
``` Aminoglycosides Cisplatin Glycopeptides (vancomycin) Loop diuretics Vinca alkaloids ```
36
What are the drugs causing serotonin syndrome?
Triptans, bupropion, buspirone, TCA, MAOI, SSRI, MAOB inhibitors (selegiline), 5HT3 antagonist (ondansetron), amfetamines, St. John’s wort
37
What are the drugs that cause peripheral neuropathy?
``` Amiodarone Cisplatin Disulfiram Phenytoin Isoniazid Metronidazole Vinka alkaloids ```
38
What are the drugs cause CNS depressant effects?
``` Alcohol Agomelatine Anaesthetics Antiepileptics Antihistamines Antipsychotics Baclofen Benzodiazepines Ketamine Melatonin Opioids Venlafaxine Z drugs ```
39
What are the drugs that cause antimuscarinic effects?
``` Antimuscarinics Atropine TCA Antihistamines Clozapine Antipsychotics ```
40
What drugs cause hypotension?
Beta blockers CCBs ACEi/ARB Alpha blockers Alcohol, dopamine receptor agonists, nitrates, diuretics, sildenafil, gliflozins, antipsychotics
41
What drugs cause first dose hypotension?
Alpha blockers ACEi/ARB Nitrates Indoramin
42
What are the drugs that cause bradycardia?
``` Beta blockers Amiodarone Digoxin Rate limiting CCBs Clonidine ```
43
What are the drugs that cause thromboembolism?
Cytotoxics - bleomycin, cyclophosphamide, thalidomide, vinca alkaloids, tamoxifen Epoietin Alfa, oestrogens, tranexamic acid
44
What are the drugs that increase the risk of bleeding?
Anti platelets - NSAID, SSRI, venlafaxine, clopidogrel, prasugrel, glycoprotein inhibitors (abciximab) Anticoagulants - warfarin, heparins, heparinoids, DOACs, fibrinolytics
45
What are the drugs that cause hypokalaemia?
``` Loop/thiazide diuretics Corticosteroids Beta 2 agonist Theophylline Stimulant laxatives Amphotericin B ```
46
What are the predisposing factors for QT prolongation?
``` Increasing age Female Cardiac disease Bradycardia Electrolyte disturbances ```
47
What drugs cause QT prolongation?
Antipsychotics- pimozide, haloperidol, quetiapine Antidepressants- citalopram/escitalopram, TCA, venlafaxine Anti-arrhythmics - sotalol, amiodarone CNS - methadone, lithium, triptans, apomorphine, ondansetron, domperidone, metoclopramide, quinine Macrolides, hydroxychloroquine, chloroquine, quinolone, ketoconazole, itraconazole
48
What drugs cause contact sensitisation?
Methotrexate Chlorpromazine Cytotoxics
49
What are the drugs that cause photo sensitisation?
Antifungals - voriconazole Tetracyclines- doxycycline, demeclocycline Co-trimoxazole, quinolones (oxacins) Hydroxychloroquine, chloroquine ``` Amiodarone PhenothiazineS Tacrolimus Topical NSAIDs Benzoyl peroxide Isotretinoin Vitamin A ```
50
What are the symptoms of myelosuppression?
Low blood count Susceptible to infection Anaemia Thrombocytopenia
51
What drugs cause osteonecrosis of the jaw?
Bisphosphonates
52
What are the drugs that cause myelosuppression?
DMARDs - methotrexate, penicillamine, gold Antiepileptics - carbamazepine, ethosuximide, lamotrigine, phenytoin Antibiotics- linezolid, chloramphenicol, dapsone, co-trimoxazole, trimethoprim Immunosuppressants- azathioprine, cytotoxics Antifolates - phenytoin, methotrexate, trimethoprim Others - aminosalicylates, carbimazole, clozapine, mirtazapine
53
What drugs cause taste disturbance?
``` ACEi Amiodarone Carbimazole Clarithromycin Lithium Metformin Metronidazole Zopiclone ```
54
What drugs cause dry mouth?
``` Antimuscarinics Antipsychotics Opioids Excessive diuretics Antihistamines Antidepressants ```
55
What drugs cause gingival hypertrophy?
Ciclosporin Nifedipine Phenytoin
56
What are the drugs that increase serum potassium?
``` ACEi/ARB Aldosterone antagonists Heparins NSAIDS Tacrolimus Triamterene Trimethoprim ```
57
What are the drugs that reduce serum potassium?
``` Aminophylline/theophylline Amphotericin B B2 agonists Corticosteroids Diuretics Stimulant laxatives ```
58
What are the drugs that cause hyponatraemia?
Carbamazepine Diuretics Antidepressants

Pre-reg Exam 2021 (79 decks)

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