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Biology4351 > drugs for whatever > Flashcards

drugs for whatever Flashcards

1
Q

(D/(*/~))(nmab)(+/-): Neostigmine

A

Indirect (~reuptake) cholinomimetic

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2
Q

(D/(*/~))(nmab)(+/-): Nicotine

A

Direct nicotinic receptor agonist

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3
Q

(D/(*/~))(nmab)(+/-): Bethanechol

A

Direct muscarinic receptor agonist

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4
Q

(D/(*/~))(nmab)(+/-): Methamphetamine

A

Indirect (*release) sympathomimetic

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5
Q

(D/(*/~))(nmab)(+/-): MAOI

A

Indirect (~reuptake) sympathomimetic

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6
Q

(D/(*/~))(nmab)(+/-): TCA

A

Indirect (~reuptake) sympathomimetic

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7
Q

(D/(*/~))(nmab)(+/-): Cocaine

A

Indirect (~reuptake) sympathomimetic

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8
Q

(D/(*/~))(nmab)(+/-): Epinephrine

A

α1, α2, β1, β2 direct adrenergic receptor agonist

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9
Q

(D/(*/~))(nmab)(+/-): NE/Levophed

A

α1, α2, β1 direct adrenergic receptor agonist

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10
Q

(D/(*/~))(nmab)(+/-): Phenylephrine

A

α1 direct adrenergic receptor agonist

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11
Q

(D/(*/~))(nmab)(+/-): Clonidine

A

α2 adrenergic receptor agonist

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12
Q

(D/(*/~))(nmab)(+/-): Dobutamine

A

β1 adrenergic receptor agonist

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13
Q

(D/(*/~))(nmab)(+/-): Albuterol/Terbutaline

A

β2 adrenergic receptor agonist

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14
Q

(D/(*/~))(nmab)(+/-): “ganglionic blockers”

A

Nn cholinergic receptor antagonist

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15
Q

(D/(*/~))(nmab)(+/-): Atracurium

A

Nm cholinergic receptor antagonist

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16
Q

(D/(*/~))(nmab)(+/-): Vecuronium

A

Nm cholinergic receptor antagonist

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17
Q

(D/(*/~))(nmab)(+/-): Succinylcholine

A

Nm cholinergic antagonist

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18
Q

(D/(*/~))(nmab)(+/-): Atropine

A

Muscarinic receptor antagonist

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19
Q

(D/(*/~))(nmab)(+/-): Glycopyrrolate

A

Muscarinic receptor antagonist

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20
Q

(D/(*/~))(nmab)(+/-): Ipratropium

A

Muscarinic receptor antagonist

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21
Q

(D/(*/~))(nmab)(+/-): Tiotropium

A

Muscarinic receptor antagonist

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22
Q

(D/(*/~))(nmab)(+/-): Propanolol

A

Beta blocker

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23
Q

(D/(*/~))(nmab)(+/-): Prazosin

A

α1 blocker

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24
Q

(D/(*/~))(nmab)(+/-): Labetalol

A

α1, β1, β2 blocker

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25
Q

(D/(*/~))(nmab)(+/-): Metoprolol

A

β1 blocker

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26
Q

(D/(*/~))(nmab)(+/-): Atenolol

A

β1 blocker

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27
Q

Name me a non-selective beta blocker

A

Propanolol

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28
Q

Give me some weirdly pseudo opposite drugs (an agonist and an antagonist)

A

NE stimulates α1, α2, β1

Labetalol blocks α1, β1, β2

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29
Q

What receptor mediates reflexive tachycardia?

A

β1 receptors

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30
Q

Name me some β1 blockers

A

Metoprolol
Atenolol
(Propanolol)
(Labetalol)

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31
Q

Name me some α1 blockers

A

Prazosin

Labetalol

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32
Q

Give me α1, α2, β1, β2 agonists in order

A

Phenylephrine
Clonidine
Dobutamine
Albuterol/Terbutaline

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33
Q

Give me our three cholinergic agonists

A

Neostigmine (~ cholinomimetic)
Nicotine (D m cholinomimetic)
Bethanechol (D m cholinomimetic)

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34
Q

Give me our three antinicotinics (m)

A

Atracurium
Vecuronium
Succinylcholine

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35
Q

Give me our four antimuscarinics

A

Atropine
Glycopyrrolate
Ipratropium
Tiotropium

36
Q

What are beta blockers never

A

Beta blockers are never vasodilators

37
Q

What is atracurium used for?

A

blocks nm junctions

flaccid paralysis

38
Q

What is vecuronium used for?

A

blocks nm junctions

flaccid paralysis

39
Q

What is succinylcholine used for?

A

blocks nm junctions

(irreversible, short term) flaccid paralysis

40
Q

What is atropine used for?

A

blocks M2 site
increases HR
treat sinus bradycardia

41
Q

What is glycopyrrolate used for?

A

blocks M3
reduce glandular activity
reduce bronchial secretions

42
Q

What is ipratropium used for?

A

blocks M3
relaxes s.m.
treats COPD

43
Q

What is tiotropium used for?

A

blocks M3
relaxes s.m.
treats COPD

44
Q

What is propanolol used for?

A

blocks β1, β2
slows HR, constricts s.m.
treats hypertension

45
Q

What is labetalol used for?

A

blocks α1, β1, β2
vasodilation, slows HR, constricts s.m.
treats emergency hypertension

46
Q

What is prazosin used for?

A

blocks α1
vasodilation
reduces blood pressure

47
Q

What is metoprolol used for?

A

blocks β1
slows HR
treats congestive heart failure

48
Q

What is atenolol used for?

A

blocks β1
slows HR
treats congestive heart failure

49
Q

What is neostigmine used for?

A

reduces ACh reuptake

reverses paralyzing blockers

50
Q

What is nicotine used for?

A

stimulates N receptors

energy boost and P/SNS enhancement

51
Q

What is bethanechol used for?

A

stimulates M3 cells

treats urinary problems

52
Q

What is meth used for?

A

increases NE release

stimulant

53
Q

What is cocaine used for?

A

reduce NE reuptake

stimulant

54
Q

What is epinephrine used for?

A

stimulates α1, α2, β1, β2

vasoconstriction, reduces SNS, increases HR, relaxes s.m.

55
Q

What is norepinephrine used for?

A

stimulates α1, α2, β1

vasoconstriction, reduces SNS, increases HR

56
Q

What is levophed used for?

A

stimulates α1, α2, β1

vasoconstriction, reduces SNS, increases HR

57
Q

What is phenylephrine used for?

A

stimulates α1

vasoconstriction

58
Q

What is clonidine used for?

A

stimulates α2

reduces SNS

59
Q

What is dobutamine used for?

A

stimulates β1
increases HR
treats heart failure

60
Q

What is albuterol used for?

A

stimulates β2
relaxes s.m.
tocolytic

61
Q

What is terbutaline used for?

A

stimulates β2
relaxes s.m.
bronchodilator

62
Q

Complete the equation: BP = ?

A

BP = CO x SVR

63
Q

Complete the equation: CO = ?

A

CO = HR x SV

64
Q

Complete the equation: SV = ?

A

Myocardial contractility x

65
Q

When does baroreceptor reflex occur?

A

Change in BP

66
Q

What group of drugs prevents the baroreceptor reflex?

A

Beta blockers

67
Q

What two conditions can the baroreceptor reflex cause?

A

Reflexive tachycardia

Reflexive bradycardia

68
Q

Specifically what receptor mediates the baroreceptor reflex?

A

β1 receptors

69
Q

Eight ways to treat hypertension!

A 
Diuretics
Beta blockers
ACE Inhibitors/ARBs
Ca++ channel blockers
Central sympatholytics
α1 blockers
Direct arterial dilators
70
Q

Name four classes of diuretics

A

Loop diuretics- Furosemide
DCT diuretics- HCTZ
K+ sparing- Ameloride, Triamterene, Spironolactone
Osmotics- Mannitol

71
Q

Name your drugs that affect angiotensin (at all)

A

Captopril
Lisinopril
LoSARtin

72
Q

Name your Ca++ channel blockers

A

Nifedipine
Amlodipine
Diltiazem
Verapamil

73
Q

Name some standalone drugs for hypertensive treatment (drugs who’s class we know like one of)

A

Central sympatholytics- clonidine
α1 blockers- prazosin
DAD- hydralazine

74
Q

Drugs to treat angina pectoris?

A

Nitrates
Beta blockers
Ca++ channel blockers

75
Q

Name your nitrates

A

Nitroglycerin

Isosorbide dintrate

76
Q

Drugs to treat hypertensive emergency

A

Labetalol

Nitroprusside Na

77
Q

Drugs to treat systolic heart failure

A

Dobutamine

Digoxin

78
Q

Generally how to treat systolic heart failure?

A

Improve contractility

Reduce workload

79
Q

Generally how to treat diastolic heart failure?

A

Increase filling time

Reduce workload

80
Q

How to reduce workload?

A

Reduce SNS activity

Reduce fluid retention

81
Q

Drugs to reduce workload

A

Diuretics
ACE Inhibitors, ARBs
Beta blockers
Nitroprusside Na

82
Q

Drugs to increase filling time

A

Beta blockers
Ca ++ Channel blockers
ACE Inhibitors/ARBs
Diuretics

83
Q

Heart drugs that affect just preload?

A

Diuretics

84
Q

Heart drugs that affect preload and afterload?

A

ACE Inhibitors, ARBs

Nitroprusside Na

85
Q

Heart drugs that affect just afterload?

A

NONE HAHAHAHAHAHAHAHAHAHAHAH

86
Q

Heart drugs that affect neither preload nor afterload?

A

Beta blockers

Biology4351 (16 decks)

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