Dyslipidaemias Flashcards

1
Q

HMG-CoA reductase inhibitor

A

Statin

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2
Q

6 types of statins

A
Atorvastatin
Lovastatin
Simvastatin
Rosuvastatin
Fluvastatin
Pravastatin
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3
Q

Use of Rosuvastatin

A

Children <8 years

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4
Q

Fluvastatin causes

A

Hepatic reactions

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5
Q

Simvastatin usage

A

Hypercholesterolemia

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6
Q

Statin not influenced by food intake and has liver metabolism

A

Simvastatin

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7
Q

Regulate gene expression and stimulate LpL

A

Fibrates

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8
Q

Usage of Fibrates

A

Mixed dyslipidaemias

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9
Q

Types of fibrates

A

Bezafibrate
Fenofibrate
Gemfibrozil

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10
Q

Contraindication in bezafibrate

A

Renal and hepatic failure

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11
Q

Fenofibrate may cause

A

Hemolysis in G6PD deficiency

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12
Q

Gemfibrozil may cause

A

Leukopenia

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13
Q

Cholestyramine

Ezetimibe

A

Cholesterol absorption inhibitors

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14
Q

Niacin

A

Reduce LDL

Increase HDL

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15
Q

Acipimox

A

Same as niacin - not diabetogenic

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16
Q

Probucol
Policosanol
Omega - 3 - fatty acids

A

Niacin derivatives