E4: Drug Abuse/Addiction Part IV Stimulants Flashcards Preview

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Flashcards in E4: Drug Abuse/Addiction Part IV Stimulants Deck (64):
1

What are the two LEGAL stimulants?

Caffiene and Nicotine

2

What is the drug of choice for MOST AMERICANS?

Caffiene

3

HOW much of each will cause Caffeine withdrawals: coffee, tea, soda?

coffee: 1 cup tea: 2 cups soda:3 cans

4

DO YOU SEE WHAT HAPPENS when you go off Caffeine???Symptoms appear within _______ of last caffeine use

12-24 hours

5

DO YOU SEE WHAT HAPPENS when you go off Caffeine???Symptoms peak at ________

20-48 hours

6

DO YOU SEE WHAT HAPPENS when you go off Caffeine???Symptoms last for _____ Headache, Flu-like symptoms, Depression, anxiety, Lethargy, fatigue

1 week

7

Cocaine is a CNS STIMULANT with ________ properties

local anesthetic

8

Cocaine is a POTENT _________

vasoCONSTRICTOR

9

Cocaine Produces profound sense of _______

euphoria

10

INTERESTING: Produces intense ________ dependency, but no _______ OR ________

psychological...tolerance OR withdrawal

11

What are the 9 signs of cocaine use?

GB-T-ND-HHAT: 1.Gingival Bleeding/Recession Max PM 2.Bone Resorption in Max PM area 3.Tremors 4.NoseBleeds 5.Dilated Pupils 6.Hypertension 7.Headache 8. Alertness 9. Talkative!

12

How long does Dilated Pupils take after Coke use?

45 minutes after use

13

NEVER give EPI within ______ of COKE use

24 hours

14

What causes Cocaine induced Gingival Necrosis?

The vasoContrictive effect of cocaine

15

What are the 3 clinical uses for AMPHETAMINES?

1.Diet Pills 2.Energy Pills 3.Tx of ADHD

16

What is the most common abused form of Amphetamine?

Methamphetamine (crystal meth)

17

How can you MAKE methamphetamine?

Cook down pseudoEphedrine (sudafed)

18

Which drug produces a LONGER duration of action: METH or COKE?

Meth

19

Amphetamines stimulate which autonomic NS?

Sympathomimetics

20

What is the drug for ADHD that blocks Reuptake of dopaminergic neurons?

Methyl-Phen-i-Date (Ritalin)

21

What do you avoid when on Methyl-Phen-i-Date (Ritalin)?

avoid vasoconstrictors

22

Which ADHD drug has minimal sympatic effect and blocks reuptake of dopaminergic neurons?

Pemoline (Cylert)

23

Which ADHD drug blocks reup of BOTH dopamine and norepi?

Dextro-amphetamine (Dexadrine)

24

What does dextroAmphetamine inhibit?

Monamine Oxidase (MAO)

25

dextroAmphetamine Enhances sympathomimetic response of epinephrine/norepinephrine SO avoid _________

vasoconstrictors!!

26

What is our only ADHD drug that is NOT an amphetamine?

A-TOM-OX-ET-INE (Straterra)

27

Atomoxetine (adhd med) (not an amphetamine) Selectively inhibits reuptake of ________ with little to no activity at OTHER reuptake or receptor sites

norepinephrine

28

Atomoxetine (adhd med) (not an amphetamine) May increase heart rate and blood pressure in presence of a pressor agent = use _________ with caution

vasoconstrictor...hmm common theme

29

COOL! What is the name for Ecstasy???

MDMA (bath salts were MDPV)...MethyleneDioxyMethAmphetamine

30

What was ecstasy first used for?

appetite suppressant

31

Ecstasy is a stimulant _______ drug that induces ______

psychedelic...euphoria

32

HOW does ecstasy induce euphoria?

alters SEROTONIN and DOPAMINE neurotransmission

33

Ecstacy Enhances self-awareness and ability to ________ and can last ________

communicate ..... Duration of action = 4-6 hours

34

What is the dental side effect of Ecstacy?

Trismus and bruxism

35

What are the 3 fatal side effects of ecstasy?

1.cardio toxicity 2.hyperthermia 3.coagulopathy

36

Which organ is affected most by ecstasy? (besides the brain yo!)

HepatoToxic

37

Can you build a tolerance to Ecstacy?

YES

38

Methamphetamine: A type of amphetamine used in the form of crystalline ________

hydrochloride...HCl (isn't that really acidic??)

39

the Medical use for meth is its ______ form which is called:

dextrorotary form---dextroMethamphetamine (Desoxyn)

40

What is dextromethamphetamine indicated for?

ADHD, Narcolepsy, obesity (short term)

41

WHAT are the 3 neurotransmitters triggered when Meth enters the brain?

1.norepi 2.dopamine 3.serotonin

42

Meth Prolongs presence of neurotransmitters in the synapse by inhibiting _______; stable against degradation

reuptake

43

WEIRD WORD: Stimulates the _______ reward pathway, causing euphoria and excitement

mesolimbic

44

The first time meth is used, the brain is flooded with _______ for INTENSE feelings of _______

dopamine.... pleasure

45

T/F brain structure and function can be altered with chronic METH use.

TRUE

46

METH: Acute physical effects = resemble "_______" response

“fight or flight”

47

Methamphetamine is NEUROTOXIC = especially to WHAT TYPE of neurons????

dopaminergic

48

WHY is meth neurotoxic to dopaminergic neurons?

Degradation of dopamine produces reactive oxygen species (“free radicals”) such as HYDROGEN PEROXIDE (get on that ketogenic diet SON!)

49

Methamphetamine users often have unusual ________ of the skin on the face, arms and legs

lesions and scabbing

50

What the hell is FORMICATION?

the sensation of insects crawling beneath the skin

51

What are the three organs attacked by Meth? (other than the brain yo!)

1.lung 2.kidney 3.liver

52

Meth: Hallucinations---Paranoia---Delusions---Thought disorders are called "_________"

amphetamine psychosis

53

What are the 4 main warning signs of a kid on meth?

1.prolonged sleep 2.moodiness 3.depression 4.suicidal

54

Meth is especially addictive when administered by ______ or ______

injected or smoked

55

Do we have drugs to help break meth addiction, like heroin?

Nope :(

56

Meth: Increasing frequency of use among ________ and young professionals

college students

57

What was the main action of Combat Methamphetamine Act of 2005?

Requires retailers who sell ephedrine, pseudoephedrine and phenylpropanolamine to keep products behind the counter

58

****Know these**** Clinical Signs of Meth Use (7)

HAD-B-MIX 1.HTN 2.Anorexia 3.Dilated Pupils 4.Bruxism 5.Moodiness 6.Increase Sweat 7.Xerostomia

59

Meth Mouth- ______ of teeth and restorative materials

Erosion

60

****Know these****Signs of Stimulant Overdose (8)

THE-HED-CH...1.Tremors 2.Hyperactive 3.Elevated Pulse 4.Hyperthermia 5.Extreme Sweating 6.Dilated Pupils 7.Cardiac Arrythmias 8.HTN

61

Nicotine is a CNS _______ and is highly _______ (both physical and psychological)

STIMULANT...addictive

62

*know* what are the 4 desired effects of nicotine?

1.increased alertness 2.muscle relaxation 3.facilitate concentration/memory 4.decreased appetite

63

**know these** What are the 8 harmful effects of Nicotine?

NIC-HOLD-P.....1. Nausea/vomiting 2. Irritability 3.Coronary Artery Disease 4. HTN 5. Oral Cancer 6. Lung cancer 7.Dizziness 8.pulse

64

Tobacco cessation requires ______ modification! Requires often __-__ attempts!

behavioral...5-8 attempts