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1

what is sudden cardiac death

an event that is non traumatic non violent and unexpected and results in sudden cardiac arrest witgin 6 hrs of normal health

2

what are your 3 different groups of things that can acuse arrhythmia causing sudden cardiac death

inherited arrhythmia syndomre
inherited cardiomyopathy
inherited multisystem disorder with cvs involvement

3

what is a multisystem disorder that can cause sudden death from arrhythmia that is neuro related

myotonic dystrophy

4

what are your 2 different brabches of arrythmogenic inherited cardiac conditions

chanelopathy or cardiomyopathy

5

what is a channelopathy causing arrhythmia sudden death

when ther is an issue with the ion channels which leads to rhythm issues

6

what is is a cardiomyopathy causing arrhythmia sudden death

when there is an issue with hearts structure that causes rhythm imbalance

7

what are the 3 main groups of cardiomyopathy

dilated
hypertrophic
arythmogenic right vent cardiomyopathy

8

tell me about early afterdepolarisation causing arrhythmia

there is abnormal depolarisation of the heart after phase 2 so the qrs widens and then ther is more risk of a random electrical activity tacking over in the heart causing a ventricular tachy

9

when we speak about early afterdepolarisation in the heart what group are we mainly talking about of arythmia conditions

prolonged qt

10

what is the main ecg change that you get on LQTS

torsades des pois

11

what are the different chanelopathies that can cause arrhythmia sudden death

congenital LQTS
brugada
catecholaminergic polymorphic ventricular tachy
short qt
progressive familial condiction disease
familial af
familial WPW

12

is long qt caused by one genetic mutation

no ther are lots of genes that can cause it

13

why do you get arrytmia in long qt

because there is that extra length of depolariation in the qrs so an extra electrical beat can kicj in - early afterdepolarisation

14

what ion channel is effected in brugada syndomre

na

15

is short qt syndrome common and who gets it

its rare as it effects young children that will die suddenly

16

what is it that causes the arrhythmia and then scd in catacholinerguc polymorphic vent tachy

release of adrenaline

17

what ion channel is mutated in congenital LQTS

k

18

what is the ecg characters that are needed to diagnose congen lqts

qt<300ms at hr <80bpm

19

what arythmia can congen long qt be assoc with

af

20

what age can congen lqt present at

any age inc young children

21

what are some of the issues with in ICD in young children with congen lqts

they are small
they may get innaprop discharges

22

how common is congen long qt

1 in 2000 people are genetic carriers

23

what is the arrhythmia that they get in congen lqts

polymorphic Vt / torsades des pois

24

what is your risk of collapse with congen lqts

5%

25

what is your risk of sudden cardiac death in congen lqts

< 1%

26

what is the main management of congen lqts

b blockers
ICD

27

to be fitted with a ICD what do you need

to have risk of sudden cardiac death >4%

28

what are the main 2 types of congen lqts and their inheritance pattenrs

romana - if isolated long qt - aut dom
jervel long neilson if deafness and long qt - aut recess

29

how do you diagnose congen long qt

ecg with corrected qt > 480ms or a sufficents shwarts score

30

what are the main subtypes of long qt

types 1-3