What type of enzyme are lysozymes?
glycosidase
What epithlial cells produce cathelicidins?
keratinocytes in the skin and epithelial cells in the lungs and intestine
What produce histatins?
parotid; sublingual and submandibular glands in the oral cavity
What is the function of histatins?
protect against fungi eg cryptococcus neoformans and c.albicans
What is innate immunity?
recognition by preformed non-specific and broadly specific effectors e.g antimicrobial enzymes and peptides and complement
What is the early induced innate response?
recruitment of effect cells and inflammation
How are C3a; C4a and C5a involved in the innate immune response?
bind to specific trimeric GPCRs which recruit phagocytes to the site of infection
What is the difference between interferon alpha and beta?
IFNa is a family of closely related proteins whereas IFNb is the product of a single gene