elearning module Flashcards

1
Q

What type of enzyme are lysozymes?

A

glycosidase

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2
Q

What epithlial cells produce cathelicidins?

A

keratinocytes in the skin and epithelial cells in the lungs and intestine

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3
Q

What produce histatins?

A

parotid; sublingual and submandibular glands in the oral cavity

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4
Q

What is the function of histatins?

A

protect against fungi eg cryptococcus neoformans and c.albicans

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5
Q

What is innate immunity?

A

recognition by preformed non-specific and broadly specific effectors e.g antimicrobial enzymes and peptides and complement

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6
Q

What is the early induced innate response?

A

recruitment of effect cells and inflammation

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7
Q

How are C3a; C4a and C5a involved in the innate immune response?

A

bind to specific trimeric GPCRs which recruit phagocytes to the site of infection

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8
Q

What is the difference between interferon alpha and beta?

A

IFNa is a family of closely related proteins whereas IFNb is the product of a single gene

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