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Flashcards in embryology/fetal Deck (15):
1

origin of anterior pituitary

Rathke's pouch (surface ectoderm)

2

embryological event underlying tetralogy of fallot

abnormal neural crest cell migration (also occurs with transposition of great vessels and truncus arteriosus)

3

congenital torticollis

MOA: birth trauma or malposition of head in utero resulting in SCM injury and fibrosis
S/S: head tilts toward affected side (chin away), soft tissue mass in neck, occurs 2-4 wks of age
Tx: therapy and stretching exercises

4

neonatal tetanus

via unclean and infected umbilical stumps
- newborns protected via IgG from placenta if mom has immunity

5

burned sugar/caramel odor in diaper

maple syrup urine disease

6

uteric bud gives rise to...

collecting system of kidney (ureters, calyces, collecting duct, renal pelvis)

7

remnant of vitelline (omphalomesenteric) duct

Menkel's diverticulum

8

small phallus, hypospadias, undescended testes at birth

5-alpha-reductase deficiency (DHT needed for development of male external genitalia)

9

prenatal diagnosis of neural tube defects

elevated alpha-fetoprotein and acetylcholinesterase (leaked CSF)

10

most common cause of fetal hydronephros

inadequate canalization of uteropelvic junction (kidney and ureter)

11

2 vitamins lacking in breast milk

D and K

12

caudal regression syndrome

due to maternal diabetes (poorly controlled)
- sacral agenesis causing lower extremity paralysis and urinary incontinence
- range from anal atresia to sirenomelia

13

vitamin to avoid if pregnant

vitamin A
- teratogenic (cleft palate, cardiac abnormalities)
- pregnancy test needed if prescribing for acne

14

2 heart conditions causing cyanosis at birth

tetralogy of Fallot and transposition of great vessels (more severe)

15

AFP amniotic fluid/maternal serum

if decreased indicates trisomy
if increased dating error or neural tube defect