Endocrine Secretion from the Gut Flashcards Preview

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Flashcards in Endocrine Secretion from the Gut Deck (25)
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1

Where are G cells located?

In the pylori antrum of the stomach

2

What do G cells secrete?

gastrin

3

What does gastrin do?

Stimulates gastric motility

4

Gastrin stimulates parietal cells to secrete what?

HCl

5

What cells secrete Somatostatin?

D cells in stomach
Delta islet cells in pancreas

6

What does Somatostatin do?

Decreases pancreatic secretion

7

Somatostatin inhibits the effect of what?

Gastric acid secretion and gallbladder contraction

8

CCK is secreted from what cells?

I cells in the SI

9

What causes CCK to be secreted?

Presence of fat in the duodenum

10

What does CCK do to the gallbladder?

Stimulates contraction and release of bile

11

CCK relaxes what?

Sphincter of Oddi and the lower (cardiac) sphincter

12

CCK inhibits what?

Gastric emptying

13

CCK also stimulates what from pancreas?

Pancreatic enzyme secretion

14

Secretin is secreted by what cells?

S cells in the intestinal crypts of Lieberkuhn

15

What does secretin do?

Stimulates the release of bicarbonate from the pancreass

16

What does secretin decrease?

Decreases gastric acid secretion

17

Gastric inhibitory peptide is secreted by what cells?

K cells in the SI

18

GIP inhibits what?

Effect of gastrin on the parietal cells in the stomach

19

What endocrine secretion resembles Glucagon?

Glucagon-like peptide

20

Glucagon-like peptide is secreted by what cells?

K cells in the duodenum AND jejunum

21

Grehlin is secreted by what cells?

P cells in the stomach

22

Grehlin is increased when? Decreased when?

Increased before meals
Decreased after meals

23

Motilin is secreted by what cells?

M cells in the duodenum

24

What does motilin control?

Cyclical movement of the gut

25

Motilin is increased in what state?

Increased in the fasting state