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MRCP Part 1 > Endocrinology > Flashcards

Endocrinology Flashcards

(62 cards)

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1
Q

DM + Obesity Dual OHA Drugs

A

Metformin + DPP4 Inhibitor

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2
Q

Cushinoid Features + Normal Dexamethasone suppression test

A

Psuedo Cushing Syndrome (Seen in Alcoholics)

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3
Q

Low sodium + Quadriparasis + Inability to swallow or speak

A

Central Pontine Myelinolysis

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4
Q

Thyroid Lymphoma Management

A

Chemotherapy + External Beam Radiotherapy

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5
Q

Amenorrhoea + Low LH and FSH

A

Hypothalamic Hypogonadism

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6
Q

Hypoglycemia with no cause identified

A

Inpatient 72 hour fasting and check insulin + C-peptide levels

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7
Q

Causes of Hypoglycemia

A

EXPLAIN
- EXogenous Drugs - Insulin,
- Pituitary Insufficiency
- Liver Failure
- Adrenal Failure
- Insulinomas
-Non-Pancreatic Neoplasms

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8
Q

Acromegaly Medical Management

A
  1. Cabergoline
  2. Octreotide
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9
Q

Differentia between MEN 1 and MEN 2

A

MEN 1 has angiofibromas not seen in MEN 2

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10
Q

SIADH Diagnosis

A
  • Serum Osmolality <275 mOsm
  • Urine Osmolality > 100 mOsm
  • Urine Sodium >30
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11
Q

Post Surgery follow up for thyroid cancer

A

TSH supression with thyroxine and dynamic risk stratification

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12
Q

Cushings Initial Investigations

A
  • 2 x 24 hour urine free cortisol
  • Overnight Dexamethasone suppression test
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13
Q

To differentiate pituitary adenoma and ectopic ACTH

A

High Dose Dexamethasone suppression test

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14
Q

Acromegaly Initial Test

A

IGF-1 Levels

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15
Q

MI + DM OHA of choice

A

SGLT2 - Empaglifozin

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16
Q

Diabetics undergoing strenuous exercise + Needs Insulin

A

Insulin Pump

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17
Q

Proximal Muscle weakness + Long Standing Diabetes

A

Diabetic Amyotrophy

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18
Q

Addisons + Amenorrhoea hormone responsible

A

Prolactin

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19
Q

Carbimazole + Sore Throat

A

Agranulocytosis

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20
Q

Elevated Parathyroid Hormone-related Protein (PTHrP) Seen in

A

Hypercalcemia of Malignancy

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21
Q

Common Type of cancer with Hypercalcemia

A

Squamous

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22
Q

On Multiple Anti hypertensives but Hypertension

A

Conn’s Syndrome

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23
Q

Amiodarone Induced Thyrotoxicosis Management

A

Antithyroid Drugs + Corticosteroids

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24
Q
  • Short Stature
  • Shortening of fourth and fifth metacarpals
  • Basal Ganglia Calcification
    Seen in
A

Pseudohypoparathyroidism

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25
Anti-Thyroid Peroxidase antibodies + Post partum
Post partum Thyroiditis
26
Anti TSH Receptor Antibody
Graves Disease
27
Pheochromocytoma management
Alpha Blocker then Beta Blocker Then Surgery
28
Cranial Nerve Palsy + Headache + Hypotension
Pituitary Apoplexy
29
Cushings Disease on ABG
Hypochloremic Metabolic Alkalosis
30
On Metformin + Risk of CVD next OHA is?
SGLT2 Inhibitors
31
Hyperthyroidism + Viral Prodrome preceding
De-Quervains Thyroiditis
32
Pheochromocytoma but no CT finding - Next Investigation
Metaiodobenzylguanidine (MIBG) Scan
33
High T4 + Low TSH + Scintigraphy shows low uptake by gland
Thyrotoxicosis Factitia
34
First Sign of Onset of Puberty in Females
Breast Bud Development
35
Female External Genitalia + Absence of hair growth + No Menses
Androgen Insensitivity Syndrome
36
Medullary Thyroid Cancer + High Blood Pressure
Phaeochromocytoma due to MEN-2a
37
OTC Antacids + Increased Ca2+ and Bicarbonate levels in blood
Milk-Alkali Syndrome
38
Adrenal Crisis Management
IV NS + IV Hydrocortisone
39
Increased Prolactin + Myxoma + Spotty Pigmentation
Carney's Syndrome
40
Young + Normal Anion Gap Metabolic Acidosis + Abdominal Pain
Addisons Disease
41
Cerebellar Hemorrhage + Retinal Angioma + Retinal Detachment
Von Hippel Lindau Disease
42
Low BMI + Young women + Strenuous Exercise + Amenorrhoea
Premature Ovarian Failure
43
Hormone Responsible for Epiphyseal Fusion and Cessation of Growth
Oestrogen
44
Hormone to test Presence of Ovulation
Luteinizing Hormone
45
Diagnosed as Type 2 DM but Urine ketones + despite OHA
Latent Autoimmune Diabetes of Adulthood
46
Lack of sense of smell + Normal Height + Small Testis
Kallmann Syndrome
47
Graves Eye Disease worsened by:
Radioiodine
48
Management of Secondary Hyperparathyroidism
Calcium and 1 alpha calcidiol
49
Glucagonoma Dermatological Finding
Necrolytic Migratory Erythema
50
ABG Finding in Hyperthyroid Patients
Decreased PaCO2
51
Pagets Disease on Bone Biopsy
Multinucleated Osteoclasts
52
Investigation to know volume thyroid
Ultrasound Scan
53
High TSH High Free T4 and T3
Poor compliance with medication
54
Bilateral Proptosis and Dysconjugate eye movement seen in
Graves Diseases (Don’t change answer even if TSH and T4 are not indicating)
55
Indication of use of Bromocriptine
Prolactinoma
56
Initial/Standard/Mainstay Treatment of Acromegaly
Trans-Sphenoidal Surgery
57
Increased Insulin Resistance how does it affect clotting
Increased levels of Plasminogen Activator Inhibitor-1
58
Diabetic on DVT Prophylaxis + Hyperkalemia cause
Heparin Treatment
59
Leptin Mechanism of Action
Stimulation of GnRH by Hypothalamus
60
Early detection of Thyroid cancer investigation
Serum Thyroglobulin
61
Pituitary hormone which falls during later stage of pregnancy
Growth Hormone
62
SGLT-2 Site of Action
Early Proximal convoluted tubule

MRCP Part 1 (17 decks)

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