Environment and Lifestyle Related Pathology Flashcards Preview

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Flashcards in Environment and Lifestyle Related Pathology Deck (3)
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1
Q

Effects of mushroom poisoning by amanita phalloides, what is the toxin?

A
  • abdominal pain, vomiting, diarrhea, fulminant hepatitis, extensive liver necrosis, coma and death
  • amanitin ▶️ (-) RNA polymerase
2
Q

Why is the basophylic stippling produced in lead poisoning?

A

Inhibition of pyrimidine 5’ nucleotidase

3
Q

Why is the microcytic anemia in lead poisoning produced?

A

Inhibition ferrochelatase and d-aminolevulinic acid dehydrase ▶️ ⬇️ heme synthesis