EX 2; Regulation of Systemic Arterial Pressure Flashcards Preview

AU14 Physiology > EX 2; Regulation of Systemic Arterial Pressure > Flashcards

Flashcards in EX 2; Regulation of Systemic Arterial Pressure Deck (22):
1

This is the sum of the resistances to flow offered by all the systemic blood vessels

TPR; total peripheral resistance

2

What is the equation for MAP

MAP = CO x TPR

3

All changes in MAP must be the result of changes in what two things

cardiac output
TPR

4

What is the equation for CO

CO = HR x SV

5

Dynamic changes in vasodilation/vasoconstriction due to changes in the resistance of these can alter the MAP

arterioles

6

This occurs to protect the maintenance of MAP

compensatory changes in arteriolar resistance

7

What is the equation for flow

change in pressure/resistance

8

Which portions of the body have their MAP regulated by local control

heart and brain
needed to control their own BP

9

What portions of the body have their MAP regulated by neuronal control

GI
skeletal muscles
epithelium, etc.

10

The sympathetic system acts upon which parts of the heart

atria and ventricles

11

Sympathetic input to the SA node is via which receptors/channels

β receptor
funny channel

12

Parasympathetic input uses this receptor/channel

muscarininc receptor
funny channel

13

Sympathetic input to the vessels is via which receptor

α receptors

14

How does the sympathetic system increase HR via the use of α and β channels

α on the vessels = vasoconstriction = increased TPR
β on ventricles = increased contractility and increased Ca = increased SV

15

Blood loss causes a reduction in MAP, which is left unchecked would result in what

rapid and irreversible damage to the brain and the heart

16

These function as sensors in the homeostatic maintenance of MAP by constantly monitoring pressure in the aortic arch and carotid sinus; *Main short term way to regulate MAP

baroreceptors

17

The action potential frequency in baroreceptor neurons is represented here as being directly proportional to what

MAP

18

Baroreceptor neurons deliver MAP information to where

the medulla oblongata's cardiovascular control center; CVCC which determines autonomic output to the heart

19

The information reported by baroreceptor neurons sets in motion autonomic responses to the heart (via CVCC) but also to where

arterioles and veins; this allows MAP to more readily be moved closer to the "set point"

20

If arterial pressure decreases, the discharge rate of the baroreceptor does what

decreases

21

What four things does a decrease in baroreceptor function induce

increased HR due to increased sympathetic activity and decreased parasympathetic activity
increased ventricular contractility (sym. activity)
arteriolar constriction (sym. activity)
increased venous contraction (sym. activity)

22

The long term way to regulate blood pressure is through the use of what

an abnormal increase in MAP "squeezes" ,pre fluid out of the blood into the urine, leading to a reduction in blood volume, thus reducing MAP to the "set point"