Exam 1 Flashcards
Looking at the body appearance e.x. Examinations
Inspection
Structure with hands e.x. Taking pulse and swollen lymph nodes
Palpation
Listening to natural sounds e.x. Heart beat and lungs
Auscultation
Taps body for abnormal resistance and listens for sounds e.x. Pockets of fluid,air,and scar tissue
Percussion
What is cadaver dissection?
Also known as anatomizing, it reveals the relationship between cutting and separating tissues.
The study of more than one species in order to examine structural similarities and differences to analyze evolutionary trends
Comparative anatomy
Anatomy is the study of
Form
Opening the body to see what is wrong e.x. Common to diagnose disorders
Exploratory surgery
Methods of viewing the body without surgery e.x. Radiology
Medical imaging
Can be seen with the naked eye without magnification
Gross anatomy
Study of structure and function of individual cells
Cytology
The study of microscopic structure of tissues
Histology (microscopic anatomy)
Fine detailed, molecular level with an electron microscope
Ultrastructure
Examine tissues for signs of disease
Histopathology
Physiology is the study of
Function
Sub-disciplines of physiology
Neuro,endocrine, and patho (disease)
What has limitations on human experimentation and is the basis for new drug developments and medical procedures?
Comparative physiology. We study different species to learn about bodily functions, e.x. Animal surgery and drug trials
Father of medicine,Hippocratic oath, and urged people to not link illness to gods or demons but natural occurrence
Hippocrates
Diseases and natural events could be caused by the supernatural (theologi) or natural (phsysici).
Complex structure are built from simple components
Aristotle
Wrote the first medical textbook
Cadaver dissections we’re banned so animals were used,hence he guessed the human anatomy
Science is a method of discovery not facts from faith
Advised followed to trust their own observations as he could be unreliable/wrong
Galen
1st to coin the term anatomy
Dissected aborted fetuses
Later only dissected animals because of the fear of the gods
Diocles of Carystus
Great anatomist
Vivisections on prisoners
Herophilus
Wrote 10 influential medical texts and became a physician to Egyptian sultan Saladin
Maimonides
“Galen of Islam”; combined Galen and Aristotle findings with own findings.
Wrote “Canon of Medicine” which was used in medical schools for some time
Avicenna
How did medicine change in the Middle Ages in Europe?
Science became severely repressed in Christian cultures,whereas in Jewish and Muslim faith they were free of inquiry.
Medicine was taught primarily as dogmatic commentary on Galen and Aristotle
There were crude medical illustrations instead of realistic depictions
What was Andreas Vesalius’ contribution?
He is the father of anatomy. He was also the first to preform own dissections than a barber-surgeon. He also was the first to publish accurate anatomical drawings.
William Harvey created
Experimental physiology and studies blood circulation, realizing that the blood flows from the heart and returns to it. He also worked with Michael Servetus.
Robert Hooke made _______ and published the first comprehensive book of microscopy called Micrographia.
Improvements to the compound scope that magnified to 30x. He also invented the specimen stage,illuminate,coarse, and fine focus controls.He also was the first to see and name ‘cells’.
Antony Van Leeuwenhoek invented ______ and published his findings of blood,lake water,sperm, and bacteria from teeth.
A simple (single-lens) microscope with great magnification to look at fabrics (200x).
Joh Hunter sought out _____
An Irish giant named Byrnes
What was the anatomy act of 1832?
It forbade body snatching for anatomical specimens.
__________ & __________ greatly improved compound microscopes and added the condenser and superior optics to eliminate blurry edges (spherical aberration) and rainbow distortions (chromatic aberration)
Carol Zeiss & Ernst Abbe
They concluded that “all organisms were composed of cells” and first proposed Cell Theory as all functions of the body are interpreted as effects of cellular activity.
Mathias Schlesinger & Theodor Schwann (Schwann cell)
Frances Bacon and Rene Descartes invented
Habits of scientific thought and sought systematic way of seeking simulators, differences, and trends in nature + drawing drawings useful generalizations from observable facts (Scientific Method)
Frances Bacon coined
Inductive reasoning as it is a way of making numerous observations until one becomes confident in generalizing and deducting with own knowledge.
- reliable observations, tested & confirmed repeatedly,and not falsified by creditable observations.
- have to have proof without a reasonable doubt
A more physiological knowledge is gained with
Hypothetical-Deductive Methods as an investigator asks a question and formulated a hypothesis, a good hypothesis consists of: previous research/knowledge, can be testable and falsifiable with evidence
The theory of natural selection was coined by Charles Darwin and discusses what?
It discusses “our origin,our nature, and place in the universe” by increasing our understanding of human form and function.
Selection pressures an hereditary advantage are
Natural selection
Change in genetic composition or population of organisms, for example, development of bacteria resistance to antibiotics of new strands of AIDS.
Evolution
The earliest primates were
Squirrel sized, arboreal, insect-eating African mammals thy moved to trees for safety,food supply and lack of competition.
What are the adaptations for arboreal (treetop) life style?
Mobile shoulders (Bette movement among branches),opposable thumbs (grasping), forward facing eyes/stereoscopic vision (depth perception to watch prey),color vision, and larger brains + good memory (remembered food sources and improved social organization)
Standing and walking on two legs which makes it easier to spot predators, carry food or infants is ___________
Bipedalism
What are some adaptations from the early primates?
Skeletal and muscular modification along with increased brain volume size and family/social changes.
The oldest bipedal primate
Australopithecus (A is the beginning of the alphabet)
Taller,larger brain volume, probable speech and tool making were the
Homo-genus (geniuses b/c tools and speech)
They migrated from Africa to parts of Asia
Homo-erectus (erect means upright and they had to walk upright to these places)
Sole surviving hominid species are the
Homo sapiens which originated in Africa
Theory that a large complex system such as the human body can be understood by studying its simpler components. This was proposed by Aristotle and is a productive approach.
Reductionism
“Emergent properties” of the whole organism that cannot be predicted from separate parts aka human are more than the sum of their parts
Holism
If a hormone cannot enter a cell, it may bind to a receptor in the plasma membrane and trigger the formation of ___ within the cell.
cAMP
When a cell takes something in by endocytosis, part of the plasma membrane is removed. The cell does not become smaller because
Golgi vesicles fuse with the membrane
If a cell doubled in diameter, it would have twice as much cytoplasm to maintain.
False
Insulin is taken up by cells lining capillaries (endothelial cells) and transported across the other side where it is released to the tissues. This transport, which captures on one side and releases on the other, is called
Transcytosis
All of the following processes allow for transport of materials across the cell membrane except
Pinocytosis
Cells of the small intestine and kidney tubule have a “brush border” composed of ___, which are cell extensions that increase surface area.
Mircovilli
In the capillaries, blood pressure forces water, salts, nutrients, and other solutes through pores in cell membranes and gaps between cells. Materials that are too large will not be able to pass easily across the capillary wall. This process that forces selected materials across the wall of a capillary is called
Filtration
The clear, structureless gel in a cell is its
cytosol
The sodium potassium pump is
A transmembrance protein
Which of the following processes could only occur in the plasma membrane of a living cell?
Active transport
Cells specialized for absorption of matter from the ECF are likely to show an abundance of
Microvilli
Aquaporins are transmembrance proteins that promote
Osmosis
Membrane carriers resemble enzymes except for the fact that carriers
Do not chemically change their ligands
The cotransport of glucose derives energy from
The sodium concentration gradient
The function of cAMP in a cell is
To activate kinases
Most celluar membranes are made by
Replication of existing membranes
The force exerted on a membrane by water is called
Hydrostatic pressure
What is true about recessive genes?
Their expression is masked in the presence of a dominant allele and only occur when both homologous chromosomes appear
During the mitotic phase called ___________ , chromosomes condense, spindle fibers form, the nuclear envelope disappears and centrioles migrate to the poles.
Prophase
Which term refers to a type of inheritance in which three or more alleles exist for the same gene?
Multiple Allele Inheritance
Cells start dividing when they snugly contact neighboring cells or when growth factors are withdrawn.
False
Eye color and skin color are traits determined by genes at multiple loci. They are examples of which type of inheritance?
Polygenic Inheritance
Which term means the transmission of genetic characteristics from parent to offspring?
Heredity
One member of each ____________ pair of chromosomes is inherited from the individual’s mother and the other from the father.
Homologous
ABO blood type is a trait that demonstrates which type of inheritance?
Multiple Allele
If the mother is a carrier for hemophilia (X-linked trait) but the father does not have this condition, what is the chance that their son will have the disease?
50%
Which type of inheritance is a phenomenon in which two or more genes contribute to a single phenotypic trait?
Polygenetic
Dominant alleles are always more common in the gene pool than recessive alleles.
False
A genotype does not inevitably produce a phenotype. Which term refers to the percentage of a population with a given genotype that actually exhibits a predicted phenotype.
Penetrance
Epigenetic Effects can cause
Cancer,obesity, and make a stem cell become a liver cell
Males are more likely than females to inherit a genetic disease if the gene for it is which of the following?
X-Linked
What is true regarding O-type blood?
It is caused by the recessive allele and individuals with this are homozygous for this trait
Which of the following occurs as the ribosome shifts down the mRNA by a distance of three nucleotides?
The tRNA that was in the P site moves into the E site.
What happens when a stop codon is encountered in the mRNA?
The ribosomal complex falls apart and the protein is released into the cell.
Which of the following statements about DNA replication is TRUE?
The leading strand is replicated continuously, while the lagging strand is replicated discontinuously.