EXAM #1: INTRODUCTION I & II Flashcards Preview

Pharmacology > EXAM #1: INTRODUCTION I & II > Flashcards

Flashcards in EXAM #1: INTRODUCTION I & II Deck (25):
1

What is the definition of pharmacology?

Science concerned with the interaction of chemical substances with a biological target

****Specifically, what are the mechanisms that counteract disease?

2

What is the definition of pharmacy?

Science and profession concerned with:

- Preparation
- Dispensing
- Proper utilization

of drug products.

3

What is toxicology?

Science of poisons and toxicity that focuses on the harmful effects of drugs/ their mechanisms

4

What is a prescription drug?

Agents whose sale is restricted and only available with an Rx from a LICENSED provider

5

What organization regulated prescription drugs at the federal level? What about the state level? What is the difference?

Federal= FDA
State= controls licensure of providers that Rx

6

Outline the fives schedules of drugs.

I= high abuse potential, no medical use*

II= high abuse potential, WITH medical use

III= less abuse potential than I or II, low potential for dependence

IV= less abuse potential and dependence than III

V= less abuse and limited dependence

7

What is a nonprescription of OTC drug?

Drugs that can be sold with directions for safe use by the public


*****Note that there is wide variation in the marketing of these drugs for substances that are v. similar

8

Are nonprescription drugs regulated?

Yes, these drugs are also monitored by the FDA

9

What are the clinical considerations regarding OTC drugs that you should keep in mind as a provider?

1) May be a CHEAPER/ useful option for a patient
2) May EXACERBATE a medical condition
3) Drug INTERACTIONS
4) May be used INAPPROPRIATELY

10

What are the three basic steps of drug development?

1) Drug identification
2) In vitro experimentation and animal testing
3) Clinical testing

11

What happens once a drug is identified?

Animal testing occurs

12

What are the purposes of animal testing?

- Drug characterization
- Determination of a lethal dose

13

What is the difference between phase I, II, III, and IV clinical testing?

I= Is the dose safe?
- Small # of patients
II= Does it work?
- Small # of patients
III= Is it better? RCT*
IV= Should it stay?
- "Post-marketing studies"

14

What are the three names that are given to a drug?

- Chemical name
- Generic name
- Trade name

15

What is the chemical name of a drug?

Standard chemical nomenclature denoting the chemical structure

16

What is the generic name of a drug?

Non-proprietary name of a drug derived from the chemical name*

*****This is the only name of a drug that will be given on boards*****

17

What is the trade name of a drug?

Registered brand name or trademark given to a specific drug

18

How are the five general methods for classifying drugs?

- Drug action
- Molecular target
- Drug source
- Chemical nature
- Generic name

19

What type of drug classification is "antiviral agent?"

Drug action

20

What type of drug classification is "Beta-Blocker?"

Molecular target

21

What type of drug classification is "atropine?"

Drug source

*****Atropine is a naturally occuring compound from the ATROPA genus of plants*****

22

What type of drug classifications are the titles, "steroids, barbiturates, benzodiazepines?"

Chemical nature

23

What type of drug classification is "atorvastatin?"

Generic name

24

What is pharmacokinetics?

"What the body does to a drug."

25

What is pharmacodynamics?

"What the drug does to the body."

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