Exam 1: Key Terms & Objectives Flashcards

1
Q

what is fibrinolysis?

A

3rd phase of hemostasis. (clot breakdown)

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2
Q

what are some of the treatment options for hyperkalemia?

A

stabilize heart with IV calcium

give IV insulin and glucose

hyperventilation

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3
Q

what is the least effective volume expander?

A

crystalloid b/c only 1/3 will remain IV

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4
Q

most common congenital bleeding disorder

A

VonWillebrand disease

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5
Q

more severe form of hemophilia?

A

B “Chirstmas Disease”

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6
Q

why shouldn’t you use LR when administering blood products?

A

it contains Ca2+ which interacts with the citrate in PRBC and initiates clotting.

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7
Q

what kind of EKG changes are seen with hypocalcemia?

A

long QT interval or heart block

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8
Q

what is the etiology of Cl- depletion alkalosis?

A

pt with low Cl- levels, will hold on to HCO3 in the kidneys and citrate in PRBCs will be converted to HCO3 in liver.

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9
Q

anatomy of nephron

A
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10
Q

adverse effects of anemia

A

reduced O2 transport; weakness; fatigue; secondary organ failure

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11
Q

pathophysiology of pheochromocytomas

A

catecholamine-secreting tumor of the adrenal medulla

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12
Q

what is in cryoprecipitate?

A

The fraction of plasma that precipitates when FFP is thawed Each bag of Cryo contains ~ 200 mg of fibrinogen and 100 units of Factor VIII (80 to 110 IU)

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13
Q

what electrolyte disturbance can cause “U waves?”

A

K+ (Hypokalemia)

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14
Q

match the following disease with its hormonal abnormality

  1. too much aldosterone
  2. hypoplasia of thymus
  3. too much cortisol
  4. deficiency of aldosterone synthetase
  5. vasopressin deficient
A
  1. Conn syndrome
  2. DiGeorge
  3. Cushing’s
  4. hypoaldosteronism
  5. Diabetes Insipidus
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15
Q

SBO (small bowel obstruction) and electrolyte disturbances

A

Causes N & V –> dehydration and loss of electrolytes (K+, Cl-, Na+)

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16
Q

pathophysiology of hemophilia A and B

A

Deficiency of FVIII = Hemophilia A Deficiency of FIX = Hemophilia B

17
Q

causes of sickle cell crisis

A

dehydration; infection; increased O2 demand

18
Q

effects of insulin the morning of surgery

A

later…………………………

19
Q

anion gap calculation

A

Na - (Cl + HCO3)

20
Q

cause of Diabetes insipidus?

A

neurogenic (lack of vasopressin secretion) or nephrogenic (decreased response to vasopressin)

21
Q

normal PT lab values

A

Normal: 10-14 seconds

22
Q

treatment for lactic acidosis

A

THAM: tromethamine & O2 delivery

23
Q

causes of respiratory acidosis

A

Alveolar hypoventilation, High PaCO2 Etiologies variable Lung disease Increased metabolic demand Multiple etiologies: neurologic, pharmacologic, trauma, sepsis, cardiac, pulmonary, etc.

24
Q

indication of autonomic neuropathy

A

can be caused by DM –> problems with orthostatic hypotension