Exam 1 Lecture 1 Flashcards Preview

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Flashcards in Exam 1 Lecture 1 Deck (53)
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1
Q

Organs of immune system

A

thymus
spleen
lymph nodes

2
Q

tissue of the immune s

A

bone marrow

lympoid tissue

3
Q

cells of the immune s

A

white blood cells

red blood calls and platelets

4
Q

soluble factors

A
complement system
antimicrobial peptides
antibodies 
cytokines
chemotoxic factors
5
Q

primary lymphiod tissue

A

bone marrow

thymus

6
Q

secondary lympoid tissues

A

spleen

lymph nodes and tissues

7
Q

bone marrow

A

where most cells undergo maturation

tissue

8
Q

thymus

A

where T cells undergo maturation

organ

9
Q

lymph nodes and tissue

A

where immune cells are ready to respond

10
Q

site of hematopoesis

A

bone marrow

11
Q

GALT

A

gut associated lymphoid tissue

12
Q

spleen

A

largest secondary lymphoid organ

traps antigens from circulation

13
Q

2 spleen regions

A

red and white pulp

14
Q

white pulp composition

A

composed of periateriolar lymphoid sheaths (PALs)

15
Q

white pulp zones

A

T cell zone
B cell zone
marginal zone

16
Q

red pulp

A

RBC cemetery

17
Q

hematopoietic stem cell differentiates into

A

common lymphoid precursor OR common myeloid precursor

18
Q

common lympoid precursor become

A

B cell OR NK/T cell precursor

19
Q

B cell becomes

A

plasma cell

20
Q

NK/T cell precursor becomes

A

T cell or NK cell

21
Q

T cell becomes

A

Effector T cell

22
Q

Plasma cell lineage

A

hematopoeitic stem cell –> common lymphoid precursor -> B cell -> plasma cell

23
Q

Effector T cell lineage

A

hematopoeitic stem celll -> common lympoid precursor -> NK/t cell precursor -> t cell -> effector t cell

24
Q

NK cell lineage

A

hematopoietic stem cell -> common lympoid precursor -> NK/ t cell precursor -> NK cell

25
Q

common myloid precursor differentiates into

A

granulocyte macrophage progenitor OR megakaryocyte/ erythroid progenitor

26
Q

megakaryocyte/erythroid progenitor differentiates into

A

megakaryocyte OR erthroblast

27
Q

megakaryocyte to

A

platelets

28
Q

erythroblast to

A

erythrocyte

29
Q

granlocyte macrophage progenitor to

A
macrophage and dendritic cell precursor 
neutorphil
eosinophil 
basophil 
unknown precursor to mast cells
30
Q

macrophage and dendritic cell precursor becomes

A

monocytes and dendritic cells

31
Q

monocytes become

A

macrophages and dendritic cells

32
Q

platelets lineage

A

hematopoietic stem cell -> common myloid precursor -> MEP (megakaryocyte/erythoid precursor) -> megakaryocye -> platelets

33
Q

erythrocyte lineage

A

hematopoitic stem cell -> common myloid precursor -> MEP (megakaryocyte/erythoid precursor -> erythroblast -> erythrocyte

34
Q

Secondary lympoid tissues

A

trap antigens that come from mucosal surfaces via M cells

35
Q

M cells

A

transport antigens to luminal lymphiod tissue via transcytosis

36
Q

GALT details

A

well organized

includes: tonsils, adenoids, Peyers patches

37
Q

BALT

A

broncial

38
Q

MALT

A

mucosal

39
Q

VALT

A

vaginal

40
Q

LALT

A

larynx

41
Q

blood makin’ in embios

A

yolk sac

42
Q

blood makin’ around 4th month

A

fetal liver +spleen

43
Q

blood makin’ after 4th monthish

A

bone marrow

44
Q

effector B cells

A

plasma cells which make antibodies

45
Q

effector T cells

A

include T helpers and cytotoxic T cells

46
Q

T helpers

A

activate and regulate immune response

47
Q

NK cells

A

cells of innate immunity, specialized for viruses

48
Q

lymphoid lineage

A

NK cells
B cells
T cells

49
Q

Myloid lineage

A

Neutrophils
Eosinophils
Basophils

monocytes
makrophages
dendritic cells

Mast cells

50
Q

Megakaryocyte and erythroid lineage

A

erythrocyte

megakaryocyte

51
Q

soluble factors of innate immun

A

complement
anitmictobial factors
acute phase proteins

52
Q

soluble factors of adaptive

A

antibodies produced buy plasma cells

53
Q

other soluble factors

A

cytokines

chemokines