Exam 1 - Objectives Flashcards Preview

Immunology BLD 434 > Exam 1 - Objectives > Flashcards

Flashcards in Exam 1 - Objectives Deck (42):
1

Define antigen and what cell(s) the term applies to.

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2

Define innate immunity and what cell(s) the term applies to.

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3

Define adaptive immunity and what cell(s) the term applies to.

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4

Define CD antigen (marker) and the cell(s) the term applies to.

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5

Define sebum and what cell(s) the term applies to.

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6

Define defensins and what cell(s) the term applies to.

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7

Define lysozyme and what cell(s) the term applies to.

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8

Define polymorphonuclear and what cell(s) the term applies to.

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9

Characterize the innate and adaptive immunity in terms of the speed of response, the amount of variability of antigen recognition, the level of specificity of antigen recognition, the ability to improve during a response and/or with repeated exposure.

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10

What are the main advantages of the adaptive immune response

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11

List the common CD markers that can be used to identify T lymphocytes (including the main subsets) and B lymphocytes.

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12

List the mature immune cell types (found in blood and tissues) that can arise from the common lymphoid progenitor.

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13

List the mature immune cell types (found in blood and tissues) that can arise from the common myeloid progenitor.

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14

Explain the relationship between monocytes and macrophages

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15

List the three polymorphonuclear leukocytes (granulocytes) found in peripheral blood, and the color of cytoplasmic granules each possesses.

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16

Define primary lymphoid tissue and what cell(s) the term applies to.

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17

Define secondary lymphoid tissue and what cell(s) the term applies to.

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18

Define lymph.

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19

Define naive lymphocyte and what cell(s) the term applies to.

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20

Define PALS (periarteriolar lymphoid sheath) and what cell(s) the term applies to.

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21

Define GALT and what cell(s) the term applies to.

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22

Define BALT and what cell(s) the term applies to.

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23

Define MALT and what cell(s) the term applies to.

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24

Define M cell.

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25

List the two tissues/organs that represent the primary lymphoid tissues.

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26

Describe how a naive lymphocyte enters a lymph node, and how it would exit if it did not stimulated by an antigen.

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27

Describe how an antigen enters a lymph node.

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28

List where T lymphocytes and B lymphocytes are primarily located in the lymph nodes and the white pulp of the spleen

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29

Define phagocyte and what cell(s) the term applies to.

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30

Define C and what cell(s) the term applies to.

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31

Define opsonin and what cell(s) the term applies to.

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32

Define anaphylatoxin and what cell(s) the term applies to.

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33

Define chemoattractant and what cell(s) the term applies to.

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34

Define complement fixation and what cell(s) the term applies to.

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35

Define CR# and what cell(s) the term applies to.

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36

Explain what is meant by the following statement: "Complement works in a cascade fashion that amplifies as it proceeds."

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37

List the major disadvantage that complement has compared to antibody in tagging pathogens for disposal.

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38

List the define the 4 main functions that the complement proteins can perform for the immune system.

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39

Name the 3 separate pathways that can trigger the complement activations and identify the first complement component(s) that bind(s) to imitate each of these pathways.

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40

Identify the actual complement proteins that are complexed together to form the C3 convertase and C5 convertase for both the classical and alternative complement pathways.

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41

Explain what the similarities and differences are between iC3 versus iC3b, as well as iC3Bb versus C3bBb. being certain to identify which are enzymatically active and which have been inactivated

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42

Identify which complement component fragment provides the greatest amount of amplification of the complement cascade, and why (i.e. C2b, C3b, C4b, C5b)

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