Exam 3- Cervix Flashcards
Where do almost all cervical neoplasias arise from?
The transformation zone between endo and ectocervix
Sub-epithelial lymphoid follicles are a feature of..?
Chlamydial cervicitis
Grading of CIN
CIN 1-3 based on how many thirds of the epithelium show neoplastic change
Cervical screening in scotland
a) first invitation
b) frequency of subsequent invitations
a) age 20
b) every three years until age 55
Action carried out for smears which are:
a) borderline/mild dyskaryosis
b) moderate/severe dyskaryosis
c) normal
d) insufficient
a) repeat in 6 months
b) colposcopy
c) return to national screening programme
d) repeat; if again insufficient, colposcopy
Stains which are used in colposcopy (2)
Acetic acid (stains abnormal areas white) and iodine
Management following colposcopy/treatment
Test of cure at 6 months: smear cytology and HPV testing. If dyskaryosis or HPV+, repeat colposcopy
Which serotypes of HPV are responsible for around 70% of cervical cancers?
16, 18 and 33
Main risk factors for CIN/cervical cancer (4)
HPV
Combined contraceptive use
Smoking
Immunosuppression
Itchy white plaques on vuvla, usually in elderly women
Lichen sclerosus
Most vulval carcinomas are what type? What do these develop from?
Squamous carcinoma. Vulval intraepithelial neoplasia
Treatment of cervical carcinoma
Likely to be curable with hysterectomy
