Exam 3 - Lecture 20: Enterobacteriaceae & Pseudomonas Flashcards

1
Q

2

What type of bacteria are enterobacteriaceae and pseudomonas?

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2
Q

2

Are enterobacteriaceae and pseudomonas spore formers or not?

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3
Q

3

Enterobacteriaceae and pseudomonas are the _____ and most ____ group of bacteria. They cause a ______.

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4
Q

3

Enterobacteriaceae and pseudomonas account for ___ of all bacteremia.

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5
Q

3

Enterobacteriaceae and pseudomonas account for _____% of all UTIs

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6
Q

3

Enterobacteriaceae and pseudomonas cause ____ infections.

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7
Q

4

Enterobacteriaceae are found in the _________.

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8
Q

4

Enterobacteriaceae are ____ and ______ pathogens, as well as important _____ pathogens.

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9
Q

4

How many species are there of enterobacteriaceae?

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10
Q

5

What are 4 common medically important enteroobacteriaceae?

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11
Q

6

What are 5 sites of infection for enterobacteriaceae?

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12
Q

7

How do lactose fermenters apoear on differential/selective media as opposed to lactose non-fermenters?

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13
Q

8

What are 5 components of the antigenic species of enterobacteriaceae?

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14
Q

8

What is K antigen?

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15
Q

8

What is H antigen?

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16
Q

8

What is O antigen?

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17
Q

8

What type of molecule is pili?

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18
Q

8

What type of activity does Lipid A have?

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19
Q

9

What are two mechanisms of pathogenesisi for enterobacteriaceae?

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20
Q

9

Enterotoxins are involved in _____ and ____.

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21
Q

9

Hemolysins have what two functions?

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22
Q

9

Enterobacteriaceae invade by penetrating the ______ and are associated with ______ infections.

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23
Q

10

Endotoxins are found in ____ bacteria.

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24
Q

10

What is the toxic moiety for endotoxins?

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25
10 Endotoxins are involved in what 5 things?
26
11 What is the lab diagnosis for E. coli?
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11 E. coli has _____ to antibiotics.
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12 What are 5 mechanisms of pathogenesis?
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12 What are siderophores?
30
12 Slime is _____ and offers a protective coat.
31
13 What does ExPEC stand for?
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13 Extraintestinal pathogenic E. coli occupy a niche in the _________ of humans.
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13 Extraintestinal pathogenic E. coli causes both _____ and _____ infections.
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13 What are 4 infections caused by ExPEC?
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13 ExPEC has acquired many ________ genes.
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13 Uropathogenic E. coli cause most ______. Specific ____ are usually involved.
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13 ExPEC causes ____ in the bladder and _____ in the kidney.
38
14 UTIs are ____% community and most _____.
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14 What are 5 clinical manifestations of E. coli?
40
14 What are 3 virulence factors involved with E. coli?
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15 Neonatal meninigitis is second only to ______.
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15 What is the source of neonatal meningitis?
43
15 What is the specific serotype involved in neonatal meningitis? What percent of strains have this serotype?
44
16 Septicemina is the leading cause of ______.
45
17 What are the 4 diarrheagenic E. coli?
46
18 What is the most important diarrheagenic E. coli?
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18 Enterohemorrhabic E. coli is seen in the _____ and is absent in the _____.
48
18 There are an estimated _____ cases in the USA annually for Enterohemorrhagic E. coli.
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18 Enterohemorrhagic E. coli in the large intestine causes ____ then _____, and _____.
50
18 What is the source of Enterohemorrhagic E. coli?
51
18 What toxins are carried by Enterohemorrhagic E. coli?
52
19 What percent of Enterohemorrhagic E. coli cause hemolytic uremic syndrome, low red blood cell count, and kidney failure due to damage to the very small blood vessels of the kidneys?
53
19 There is ____% mortality seen with Enterohemorrhagic E. coli. There are ____ fatal cases per year.
54
19 Most isolates of Enterohemorrhagic E. coli are serotype ______.
55
19 What is the lab diagnosis used for Enterhemorrhagic E. coli?
56
19 The treatment for enterohemorrhagic DNA is _____. Do not use ______!
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22 What causes gastroenteritis?
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22 Gastroenteritis has a ____ hour incubation period and is ____.
59
22 What are 4 symptoms seen in gastroenteritis?
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22 Gastroenteritis accounts for ____% of all food borne infections.
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23 What causes enteric fever (typhoid fever)
62
23 What are 6 symptoms of enteric fever?
63
24 What causes bacteremia with or without gastroenteritis?
64
24 What are 2 predisposing factors to bacteremia caused by Salmonella?
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25 There are an estimated _____ cases per year of Salmonella in the US.
66
25 There are an estimated ____ fatal cases per year of Salmonella.
67
25 In what age group and season is Salmonella most commonly seen?
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25 What are two sources of Salmonella?
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25 What is the most common of the 6 subspecies of Salmonella?
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26 What is required for pathogenes of Salmonella?
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26 Salmonella invades _____ cells.
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26 Salmonella has bacteremic spread or control by ______ tissue.
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29 _____ therapy can be used for serious and/or disseminated Salmonella infections.
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29 What does Shigella cause?
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31 What is a key clinical manifestation of Shigellosis?
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32 What is the source for Shigella?
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34 What is the inoculum of Shigella compared to that of Salmonella?
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34 Shigella invades _______ cells.
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34 How is Shigella spread?
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34 Shigella causes damage to the _______.
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34 Shigella rarely involves the ______.
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35 What is used to prevent spread of Shigella?
83
36 What are two major symptoms of Yersina enterocolitica infection?
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36 Yersina enterocolitica is distributed ______.
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36 Yersina entercolitica can be ingested through ______, ______, and ______.
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37 What does Yersina pestis cause?
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37 What are four symptoms of bubonic plague?
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37 What is the mortality percentage for bubonic plague?
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37 What is one symptom caused by pneumonic Yersina pestis?
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40 What is the source of Yersina pestis?
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40 There are ______ reported cases per year worldwide of Yersina pestis.
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40 There are ____ cases per year in the US of Yersina pestis.
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40 Yersina pestis (pneumonic) is transmitted ______.
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42 What is one thing that is cultured with Yersina pestis?
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44 Klebsiella, Enterobacter, Serratia, Proteus, Citrobacter, Morganella are all examples of what type of bacteria?
96
44 What are 4 types of infections caused by Enterobacteriaceae?
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44 What are two sources of Enterobacteriaceae?
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44 Enterobacteriaceae are usually _____ and often ______.
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44 What is the treatment for Enterobacteriaceae?
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45 Pseudomas is a _____ group.
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45 Pseudomonas is found in what 5 places?
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45 Pseudomonas are _____ and _______pathogens.
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45 Are pseudomonas antibiotic resistant?
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46 Pseudomonas are similar to _____ in many ways.
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46 What are three types of Pseudomonas?
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47 Is pseudomonas aeruginosa oxidase positive or negative?
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47 Is pseudomnonas aeruginose oxidase positive or negative?
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47 Pseudomonas aeruginosa has a _______ pigment and a _____ odor.
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47 Is pseudomonas aeruginosa antibiotic resistant or not?
110
47 What are three places that psuedomonas aeeruginosa can be found?
111
47 Pseudomonas aeruginosa colonizes ______.
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48 Pseudomonas aeruginosa pathogenesis requires _________.
113
48 What is the name of the Pseudomonas aeruginosa caosule?
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48 What enzymes are involved in pathogenesis of pseudomonas aeruginosa?
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48 What is the exotoxin in pseudomonas aeruginosa and what does it inhibit?
116
50 What is the general shape of pseudomonas aeruginosa?
117
51 What are 6 risk factors for disease with psuedomonas aeruginosa?
118
52 Pseudomonas aeruginosa is seen in ______ contamination.
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54 What is the disease associated with pseudomonas aeruginosa?
120
54 Bacteremia by pseudomonas aeruginosa is the ____ most common cause of _______.
121
55 What is an example of a skin lesion associated with pseudomonas aeruginosa?
122
57 What are 3 diseases associated with pseudomonas aeruginosa?
123
58 What is the lab diagnosis for pseudomonas aeruginosa? What three things are being looked for?
124
59 What type of bacteria is Burkhoderia cepacia?
125
59 Is Burkholderia cepacia aerobic?
126
59 Burkholderia cepacia is glucose _______.
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59 Burkholderia cepacia is resistant to ______.
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59 Burkholderia cepacia was first described by Burkholder in 1950 as a pathogen of ______.
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59 Burkholderia cepacia is a highly virulent organism known as the ______.
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59 Burkholderia cepacia is commonly isolated from ____, _____, _______, and survives for ______.
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60 What are two diseases caused by Burkholderia cepacia?
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________ are susceptible to Burkholderia cepacia?
133
60 What are 3 diseases that Burkholderia cepacia are involved in?
134
61 Stenotrophomonas maltophilia causes _____ infections.
135
61 Stenotrophomonas maltophilia is seen in the _____ and _____.
136
61 What is the treatment for stenotrophomonas maltophilia?
137
62 S. maltophiliais is a ______ organism.
138
137 S. maltophiliais in a hospital setting is isolated from what 4 things?
139
137 S. maltophiliais is resistant to newer-generation _______.