Exam #3: Lymphatic Tissue & Organs Flashcards Preview

Cell & Tissue Biology > Exam #3: Lymphatic Tissue & Organs > Flashcards

Flashcards in Exam #3: Lymphatic Tissue & Organs Deck (25):
1

What are the 2 zones of a secondary lymphatic nodule?

1) Mantle Zone, which is dark staining & contains small mature lymphocytes
2) Germinal Zone, which is light staining & contains medium to large size & immature lymphocytes

2

Solitary Lymphatic Nodule

Temporary

3

Aggregate Lymphatic Nodule

Permanent

4

Where are aggregates of lymphatic nodules located?

- Lymph nodules (tonsils, spleen, & lymph nodes)
- Peyer's Patches
- Appendix
- BALT

5

What are tonsils?

Aggregates of lymphatic nodules that contain B-lymphocytes

6

Pharyngeal Tonsils

Respiratory/ Pseudostratified Columnar Epithelium with cilia

7

Palatine Tonsils

Nonkeratinized stratified squamous epithelium

8

Lingual Tonsils

Nonkeratinized stratified squamous epithelium

9

Cell types associated with reticular fibers

- Dendritic cells (APC)
- Macrophages (phagocytic)
- Follicular Dendritic Cells (bind antigen/antibody complexes)

10

Cortex of a lymph node

B-lymphocytes

11

Deep Cortex of a lymph node

- T-lymphocytes
- HEV

12

Medulla of a lymph node

Medullary cords

13

How does the thymus differ from lymph nodes?

- No afferent lymphatic vessels
- No 3D reticular network
- No lymphatic nodules
- No B-lymphocytes
- No sinuses

14

Type I epitheloreticular cells

- Form a seal around the cortex of the thymus, separating it from the CT capsule & trabeculae
- Contain occludens junctions

15

Type II epitheloreticular cells

- Form a meshwork in the midcortex
- Contain desmosomes
- Involved in thymic eduction

16

Type III epithelioreticular cells

- Deep cortex
- Occulens junctions
- Form a seal between the cortex & the medulla

17

Type IV epithelioreticular cells

- Associated with Type III cells & participate in establishment of the barrier at the corticomedullary junction

18

Type V epithelioreticular cells

- Form the meshwork of the medulla

19

Type VI epithelioreticular cells

- Hassall's Corpuscles
- Contain mature T-lymphocytes

20

Layers of the blood thymus barrier

1) Endothelium
2) Basal Lamina
3) Macrophages
4) Type I epithelioreticular cells

21

DiGeorge Syndrome

- Individuals cannot produce T-lymphocytes
- Lack "cell-mediated" immunity
(Also, do not have parathyroid glands & may die from tetany)

22

PALS

- Periarterial lymphatic sheath (PALS)
- Tunica adventitia of trabecular arteries infiltrated with T-lymphocytes

23

Splenic Circulation

1) Splenic artery
2) Trabecular artery
3) Central artery w/ PALS (tunica adventitia w/ T-lymphocytes)
4) Penicillar arteries (no PALS)
5) Arterial capillaries
6) Splenic sinuses
7) General circulation

24

White Pulp

- Stains blue with hematoxylin
- PALS (T-lymphocytes)
- Splenic Nodules (B-lymphocytes)

25

Red Pulp

- Stains red with eosin
- Splenic Cords- Filter blood
- Splenic Sinuses