Exam #4: Respiratory Tract Infections Review Flashcards Preview

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Flashcards in Exam #4: Respiratory Tract Infections Review Deck (38):
1

What are the normal flora of the nasopharynx?

Streptococcus viridans
Moraxella catarrhalis
Bacterioides

2

What is the only obligate anaerobe that is part of the normal flora of the URT?

Bacterioides

3

What are the bacterial pathogens that invade the URT?

Streptococcus pneumoniae
Haemophilus influenza
Neiseria meningititis
Moraxella catarrhallis

4

What are the virulence factors associated with Streptococcus pyogenes?

M-protein (degrades complement C3b)
Capsule (some, contains HA)
SPEs

5

What are the virulence factors associated with Streptococcus pneumoniae?

Polysaccharide capsule
IgA protease

6

How is strep throat treated?

PCN
Erythromycin

7

How is Diphtheria prevented? How is Diphtheria treated?

Prevention= toxoid vaccine
Treatment=
- PCN
- Erythromycin
- Antitoxin

8

What are the causative organisms of conjunctivitis?

S. pneumoniae
HiB

9

How is conjunctivitis treated?

Gentamicin
Ciprofloaxin

10

What are the causative agents of OM & sinusitis?

S. pneumoniae
HiB
M. catarrhalis

11

How are OM & sinusitis treated?

Ampicillin

12

How are C. trachomatis infections treated?

Macrolide
Tetracycline
Levofloxin

13

Which of the causative agents of typical pneumonia produces extended spectrum beta-lactamases?

Klebsiella pneumoiae

14

Which of the causative agents of atypical pneumonia does not contain peptidoglycan?

Mycoplasma pneumoniae

15

Which of the causative agents of atypical pneumonia is a parasite of amoebas?

Legionella pneumophila

16

What are the virulence factors associated with streptococcus pneumoniae?

Surface adhesins
IgA protease
Pneumolysin
Teichoic acid & peptidoglycan
Capsule

17

What are the virulence factors associated with Staphylococcus aureus?

Coagulase
Protein A
PVL

18

What are the virulence factors associated with Klebsiella pneumoniae?

LPS (endotoxin)
Capsule

19

What are the virulence factors associated with Pseudomonas aeruginosa?

Toxin A
Leukocidin
PLC
Capsule
Pyocyanin
Pyoverdin

20

What are the virulence factors associated with Mycoplasma pneumoniae?

P1 Adhesin
IgM interaction-->anemia

21

What are the virulence factors associated with Haemophilus influenza B?

PRP
LPS
IgA protease

22

What are the virulence factors associated with Bordatella pertussis?

Filamentous Hemagglutinin
Pertussis Toxin

23

How is typical pneumoniae caused by S. pneumoniae treated?

PCN or macrolide (e.g. azithromycin)
Severe= azithromycin & cephalosporin

24

How is S. aureus infections treated? What about MRSA?

Non-MRSA= PCN & cephalosporin
MRSA= Linezolid or vancomycin

25

How is Klebsiella pneumoniae treated?

Getamycin/ cephalexin
Tobramycin/ampicillin

26

How is Pseudomonas auerginosa treated?

Ticracillin or piperacillin & amikcain

27

How is Mycoplasma pneumoniae treated?

Tetracycline & erythromycin

28

How is Chlamydophila pneumoniae treated?

Tetracycline & erythromycin

29

How is Legionella pneumphila treated?

Macrolide or fluoroquinolone

30

How is Haemophilus influenza B treated?

Severe= cephalosporin
Mild= amoxicillin

31

How is Bortadella pertussis treated?

Macrolides

32

How is TB treated?

2 months of:
Isoniazid
Ethambutol
Pyrazinamide
Rifampin

26 months of:
INH
Rifampind

33

What bacteria cause laryngitis, tracheitis, & epiglottitis?

Group A Strep (S. pyogenes)
Haemophilus Influenza B
Staphylococcus aureus

34

What causes bacterial bronchitis?

Mycoplasma pneumoniae

35

Outline the four stages of pertussis infection.

1) Incubation= 7-10 days asymptomatic
2) Catarrhal= 1-2 weeks of "common cold"
3) Paroxysmal= 2-4 weeks of whooping cough & post-tussive emesis
4) Convalescent= 3-4 weeks of improved cough but severe complications--pneumonia, seizures, encephalopathy

36

What bacteria typically cause bacterial influenza associated pneumonia?

Streptococcus pneumoniae
Staphylococcus aureus
Haemophilus influenza

37

Aside from being the only DNA virus to cause the common cold, what else is unqiue about the adenovirus?

Contains adenoviral fiber proteins that are used for attachment & are toxic to cells

38

What is the Coxsackievirus associated with aside from the common cold?

Herpangina
Hand-foot & mouth
Meningitis

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