Flashcards in Exam V: CNS II Deck (11):
Which negative effect causes the patient to be unable to experience pleasure?
Alogia and anhedonia are two negative symptoms caused by blockade of which pathway?
Negative vs. Positive Effects
Negative: affect flattening (lack of emotional expression), alogia (failure/slow to respond), avoliton (loss of activity), and anhedonia (unable to derive pleasure)
Positive: agitation, delusions, disorganized speech, disorganized thinking, hallucinations, and insomnia
Manifestation of dry mouth, trouble urinating, and constipation are caused by which mechanism?
Muscarinic cholinoceptor blockage
In atypical anti-psychotic drugs, what is the mechanism of action?
High affinity for 5-HT2 serotonin receptors
Which atypical anti-psychotic drug has the least effect on weight gain?
What anti-psychotic effect causes Parkinson’s symptoms?
D2 dopamine receptor blockage in the nigrostriatal pathway
What is the emergency situation that begins with extreme muscle rigidity and uncontrollable BP?
NMS - Neuroleptic Malignant Syndrome
Which anti-psychotic causes agranulocytosis/leukopenia (decreased WBC)?
Which NT is schizophrenia associated with?