Exam V: CNS II Flashcards Preview

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Flashcards in Exam V: CNS II Deck (11):
1

Which negative effect causes the patient to be unable to experience pleasure?

Anhedonia

2

Alogia and anhedonia are two negative symptoms caused by blockade of which pathway?

Mesocortical

3

Negative vs. Positive Effects

Negative: affect flattening (lack of emotional expression), alogia (failure/slow to respond), avoliton (loss of activity), and anhedonia (unable to derive pleasure)

Positive: agitation, delusions, disorganized speech, disorganized thinking, hallucinations, and insomnia

4

Manifestation of dry mouth, trouble urinating, and constipation are caused by which mechanism?

Muscarinic cholinoceptor blockage

5

In atypical anti-psychotic drugs, what is the mechanism of action?

High affinity for 5-HT2 serotonin receptors

6

Which atypical anti-psychotic drug has the least effect on weight gain?

Ziprasidone

7

What anti-psychotic effect causes Parkinson’s symptoms?

D2 dopamine receptor blockage in the nigrostriatal pathway

8

What is the emergency situation that begins with extreme muscle rigidity and uncontrollable BP?

NMS - Neuroleptic Malignant Syndrome

9

Which anti-psychotic causes agranulocytosis/leukopenia (decreased WBC)?

Clozapine

10

Which NT is schizophrenia associated with?

Dopamine hyperactivity

11

Which atypical anti-psychotic causes the least amount of side effects?

Ziprasidone