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1
Q

What are the general features of nematodes?

A
Round worms
outer cuticle
M+F
para or free living
Anal orific
buccal cav
GI coelom
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2
Q

2 main types of nematodes are

A

small (cyatho) and large strongyles

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3
Q

Desc the Life cycle of F. hepatica

A
Indirect
intermediate host - galba truncatula
Eggs in faeces
Hatch to miracidium ––> snail
In snail replicate ––> cercaridae
cercaridae in pasture –––> metacercaridae
Metacercardiae eaten
haemhorragic tracts to liver
Mature in bile ducts
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4
Q

Tx fasciola

A

Triclabendazole (all stages~)
AR developing
Test only show adults stages (ELISA, FEC)

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5
Q

Desc the lifecycle of Cyathostomin (small red worms)

A
direct l–cycle
non–migratory (unlike L strongyles!)
eggs --> poo and hatch (L1-EL3 and iL3)
long tail to wrap around grass
EL3 or iL3 get eaten (can hypobiose)
burrow into gut mucosa --> L4
L5 in colon lumen lay eggs (=adults)
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6
Q

L Strongylus spp

A

Indirect lifecycle
migratory
iL3

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7
Q

desc properties of Toxoplasma Gondii

A
intracellular
apicomplexan
def host – cats
intermediate host – anything warm
sheep – white lesion on cotyledons
Toxovax
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8
Q

what is hypobiosis

A

cyathostomins stop development in gut mucosa until more favourable conditions occur. (EL3 and iL3). over winter.

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9
Q

Why can L3 cyathostomins survive poor conditions

A

ensheathed so wont dehydrate. will survive if no frost

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10
Q

when is peak cyathos shedding

A

august

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11
Q

what are the general features of trematodes

A
indirect
need intermediate host
no body cavity
hermaphrodite
only oral sucker
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12
Q

how can you tell difference between S. vulgaris and S. equinus

A

S. vulgaris = buccal teeth (mickey mouse)

S equinus = non

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13
Q

what are clinical sign of cyathostominosis and when is it normally seen?

A
!early spring!
kg loss
larvae in poo
colic
d++
oedema
collapse
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14
Q

how can you prevent cyathostomins?

A

rotate, strip graze, sheep alt
older horses more resist-put on dodgey pasture
correct use of antihelmintics

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15
Q

what tx are avail for cyathostomins

A
IVM = adult
MOX = mucosal stages
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16
Q

what is the best flukicidal?

A

triclabendazole

active against all stages in host

17
Q

how can adult fluke stay in bile duct

A

spikes - irritate

18
Q

what colour of fasciola eggs

A

yellow - bilirubin bile salt

19
Q

how are circariae adapted for life outside of snail and out of water

A

cuticle. can also overwinter (wo frost)

20
Q

whats the difference between cicraraie and metercercariae?

A

calcium coat to stick to grass

21
Q

what are thre 3 types of fasciolosis?

A

acute - juveniles, ingested rapidly, warm and wet conditions
subacute - both
chronic - adults ingested over longer period, cold and dry conditions so lower numbers

22
Q

what is the clinical signs of fascioliss?

A
kg loss
weak
abdo pain
death (acute)
anaemia
oedema (chronic)
23
Q

how can fasciola numbers be controlled

A

avoid wet pastures at vital times (eg when snail pop in high in summer, winter is fine!) if wet and warm - def avoid!
quarentine new stock
drain fields

24
Q

describe the lifecycle of toxoplasma

A

prey have bradyzoites in brain and muscle
cat eats
brady –> oocyst in cat gut
shed in poo - then sporolates
infest intermediate host (prey, us etc..)
sporolated oocysts infect mphages and travel in body
in gut –> mature to tachyzoites
tachy asexuallt replicate –> bradyzoites and form cysts in neuro/muscle tissue