Extra prostate (most in Quizlet)

Question 1

when to refer on 2WW for cancer

Answer 1

• feels malignant on DRE

- PSA >50-69

Question 2

rx non-metastatic disease (5)

Answer 2

• WW (conservative rx of pts unsuitable for rx)
• active surveillance (regular monitoring of pts who might benefit from future rx)
• surgery (radical prostectomy)
• radiotherapy - alternative to surgery. can be curative
• cryotherapy

Question 3

rx w/ mets

Answer 3

options

• bilateral orchidectomy (surgical castration)
• antiandrogen therapy e.g. LH releasing hormone agonist or antiandrogens
• chemo: if mets castrate resistant prostate cancer

Question 4

e.g. LHRH agonist

Answer 4

goserelin

Question 5

e.g. antiandrogen

Answer 5

bicalutamide

Question 6

hormone therapy SEs

Answer 6

flare pheonomenan (bone pain, acute bladder outlet obstruction, spinal cord compression, hypercoag, obstructive AKI

• hot flushes
• sexual dysfunction
• osteoporosis
• gynaecomatstia
• fatigue