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GI > FA GI regulatory substances & secretory products > Flashcards

FA GI regulatory substances & secretory products Flashcards

1
Q

Source of CCK

A

I cells in the duodenum and jejunum

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2
Q

Source of gastrin

A

G cells in the antrum of the stomach

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3
Q

Source of GIP

A

K cells in the duodenum and jejunum

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4
Q

Source of motilin

A

Small intestine

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5
Q

Source of secretin

A

S cells in the duodenum

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6
Q

Source of somatostatin

A

D cells of the pancreatic islets and GI mucosa

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7
Q

Source of VIP

A

Parasympathetic ganglia in sphincters, gallbladder, and small intestine

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8
Q

Source of intrinsic factor

A

Parietal cells in the body of stomach

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9
Q

Source of gastric acid

A

Parietal cells in the body of stomach

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10
Q

Source of pepsinogen

A

Chief cells in the body of stomach

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11
Q

Source of bicarb

A

Mucosal cells (stomach, duod, salivary glands, pancreas) and Brunner glands (duod)

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12
Q

CCK action (4)

A

–> pancreatic secretion
–> GB contraction
dec gastric emptying
–> sphincter of Oddi relaxation

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13
Q

Gastrin action (3)

A
  • -> gastic H+ section
  • -> growth of gastric mucosa
  • -> gastric motility
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14
Q

GIP action (2)

A

Exocrine: dec gastric H+ secretion
Endocrine: inc insulin release

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15
Q

Motilin action

A

Produces migrating motor complexes (MMCs)

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16
Q

Secretin action

A
  • -> pancreatic bicarb secretion
  • dec gastric acid secretion
  • -> bile secretion
17
Q

Somatostatin action in GI

A

dec

  • gastric acid & pepsinogen
  • pan & SI fluid secretion
  • GB contraction
  • insulin & glucagon
18
Q

NO action in GI

A

smooth muscle relaxation, including LES

19
Q

VIP action

A
  • Intestinal water and electrolye secretion

- relaxation of intestinal smooth muscle and sphincters

20
Q

intrinsic factor action

A

required for B12 uptake in terminal ileum

21
Q

Gastic acid action

A

decrease stomach pH

22
Q

Pepsin action

A

protein digestion

23
Q

Bicarb action

A

neutralize acid

GI (3 decks)

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