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Flashcards in FA - Pharmacology III Deck (80):
1

Cutaneous flushing?

1. Vancomycin.
2. Adenosine.
3. Niacine.
4. CCBs.
5. Echinocandins.
VANCE.

2

DCM?

Anthracyclines (eg doxo daunorubicin) - PREVENT WITH DEXRAZOXANE.

3

Torsades?

1. Antiarrhythmics (IA, III).
2. Antibiotics (eg macrolides).
3. Antipsychotics (eg haloperidol).
4. Antidepressants (eg TCAs).
5. Antiemetics (eg ondansetron).

4

Drug reactions - Endocrine/reproductive - Adrenocortical insufficiency?

HPA suppression 2o to glucocorticoid withdrawal.

5

Hot flushes?

1. Tamoxifen.
2. Clomiphene.

6

Hyperglycemia?

1. Tacrolimus.
2. PIs.
3. Niacin.
4. HCTZ.
5. Steroids.

7

Hypothyroidism?

1. Li.
2. Amiodarone.
3. Sulfonamides.

8

Drug reactions - GI - Acute cholestatic hepatitis, jaundice?

Erythromycin.

9

Diarrhea?

1. Acamprosate.
2. Acarbose.
3. AChE inhibitors.
4. Colchicine.
5. Erythromycin.
6. Ezetimide.
7. Metformin.
8. Misoprostol.
9. ORLISTAT.
10. Pramlintide.
11. Quidinide.
12. SSRIs.

10

Focal to Massive hepatic necrosis?

1. Halothane.
2. Amanita phalloides (death cap mushroom).
3. Valproic acid.
4. Acetaminophen.

11

Hepatitis?

1. Rifampin.
2. INH.
3. Pyrazinamide.
4. Statins.
5. Fibrates.

12

Pancreatitis?

1. Didanosine.
2. Steroids.
3. Alcohol.
4. Valproic acid.
5. Azathioprine.
6. Diuretics = Furosemide + HCTZ.

13

Pill-induced esophagitis?

1. Tetracyclines.
2. Bisphosphonates.
3. K.
4. Chloride.

14

Pseudomembranous colitis?

1. Clindamycin.
2. Ampicillin.
3. Cephalosporins.

15

Pill-induced esophagitis - Caustic effect minimized with ...?

UPRIGHT POSTURE AND ADEQUATE WATER INGESTION.

16

Drug reactions - Hematologic - Agranulocytosis?

1. Clozapine.
2. Carbamazepine.
3. PTU.
4. Methimazole.
5. Colchicine.
6. Ganciclovir.

17

Aplastic anemia?

1. Carbamazepine.
2. Methimazole.
3. NSAIDs.
4. Benzene.
5. Chloramphenicol.
6. PTU.

18

Direct Coombs (+) hemolytic anemia?

1. Methyldopa.
2. Penicillin.

19

Gray baby syndrome?

Chloramphenicol.

20

Hemolysis in G6PD deficiency?

1. INH.
2. Sulfonamides.
3. Dapsone.
4. Primaquine.
5. Aspirin.
6. Ibuprofen.
7. Nitrofurantoin.

21

Megaloblastic anemia?

1. Phenytoin.
2. MTX.
3. Sulfa drugs.

22

Thrombocytopenia?

HEPARIN.

23

Thrombotic complications?

1. OCPs.
2. HRT.

24

Drug reaction - Musculoskeletal/skin/Connective tissue - Fat redistribution?

1. PIs.
2. Steroids.

25

Gingival hyperplasia?

1. Phenytoin.
2. CCBs.
3. Cyclosporine.

26

Hyperuricemia?

1. Pyrazinamide.
2. Thiazides.
3. Furosemide.
4. Niacin.
5. Cyclosporine.

27

Myopathy?

1. Fibrates.
2. Niacin.
3. Colchicine.
4. Hydroxychloroquine.
5. IFN-alpha.
6. Penicillamine.
7. Statins.
8. Steroids.

28

Osteoporosis?

1. Steroids.
2. Heparin.

29

Photosensitivity?

1. Sulfonamides.
2. Amiodarone.
3. Tetracyclines.
4. 5-FU.

30

Rash (SJS)?

1. Anti-epileptic drugs (especially LAMOTRIGINE).
2. Allopurinol.
3. Sulfa drugs.
4. Penicillin.

31

SLE-like syndrome?

1. Sulfa drugs.
2. Hydralazine.
3. INH.
4. Procainamide.
5. Phenytoin.
6. Etanercept.

32

Teeth discoloration?

Tetracyclines.

33

Tendonitis, tendon rupture, and cartilage damage?

Fluoroquinolones.

34

Drug reactions - Neurologic - Cinchonism?

1. Quinidine.
2. Quinine.

35

PD-like syndrome?

1. Antipsychotics.
2. Reserpine.
3. Metoclopramide.

36

Seizures?

1. IHN (vit B6 def).
2. Bupropion.
3. Imipenem/cilastatin.
4. Tramadol.
5. Enflurane.

37

Tardive dyskinesia?

1. Antipsychotics.
2. Metoclopramide.

38

Drug reactions - Renal/GU - DI?

1. Li.
2. Demeclocycline.

39

Fanconi syndrome?

1. Tenofovir.
2. Ifosfamide.

40

Hemorrhagic cystitis?

1. Cyclophosphamide.
2. Ifosfamide.

41

Interstitial nephritis?

1. Methicillin.
2. NSAIDs.
3. Furosemide.

42

SIADH?

1. Carbamazepine.
2. Cyclophosphamide.
3. SSRIs.

43

Drug reactions - Respiratory - Dry cough?

ACEIs.

44

Pulm. fibrosis?

1. MTX.
2. Nitrofurantoin.
3. Carmustine.
4. Bleomycin.
5. Busulfan.
6. Amiodarone.

45

Drug reactions - Multiorgan - Antimuscarinic?

1. Atropine.
2. TCAs.
3. H1-blockers.
4. Antipsychotics.

46

Disulfiram-like reaction?

1. Metronidazole.
2. Certain cephalosporins.
3. Griseofulvin.
4. Procarbazine.
5. 1st gen sulfonylureas.

47

Nephrotoxicity/ototoxicity?

1. Aminoglycosides.
2. Vancomycin.
3. Loops.
4. Cisplatin.

48

Cisplatin toxicity may respond to ...?

AMIFOSTINE.

49

CYP450 - Inducers:

1. Chronic alcohol.
2. St.John's wort.
3. Phenytoin.
4. Phenobarbital.
5. Nevirapine.
6. Rifampin.
7. Griseofulvin.
8. Carbamazepine.

50

CYP450 - Substrates?

1. Anti-epileptics.
2. Theophylline.
3. Warfarin.
4. OCPs.

51

CYP450 Inhibitors?

1. Acute alcohol abuse.
2. Ritonavir.
3. Amiodarone.
4. Cimetidine/ciprofloxacin.
5. Ketoconazole.
6. Sulfonamides.
7. INH.
8. Grapefruit juice.
9. Quinidine.
10. Macrolides (except azithromycin).

52

Sulfa drugs:

1. Sulfonamide antibiotics.
2. Sulfasalazine.
3. Probenecid.
4. Furosemide.
5. Acetazolamide.
6. Celecoxib.
7. Thiazides.
8. Sulfonylureas.

53

Patients with sulfa allergies may develop ...?

1. Fever.
2. UTI.
3. SJS.
4. Hemolytic anemia.
5. Thrombocytopenia.
6. Agranulocytosis.
7. Urticaria (hives).
--> Symptoms range from mild to life-threatening.

54

Drug names - Antimicrobial - -azole?

Ergosterol synthesis inhibitor (ketoconazole).

55

-bendazole?

Antiparasitic/antihelminthic (mebendazole).

56

-cillin?

Peptidoglycan synthesis inhibitor (ampicillin).

57

-cycline?

Protein synthesis inhibitor (tetracycline).

58

-ivir?

Neuraminidase inhibitor (oseltamivir).

59

-navir?

Protease inhibitor (ritonavir).

60

-ovir?

DNA pol inhibitor (acyclovir).

61

-thromycin?

Macrolide antibiotic (azithromycin).

62

Drug names - CNS - -ane?

Inhalational general anesthetic (halothane).

63

-azine?

Typical antipsychotic (thioridazine).

64

-barbital?

Barbiturate (phenobarbital).

65

-caine?

Local anesthetic (lidocaine).

66

-etine?

SSRI (fluoxetine).

67

-ipramine, -triptyline?

TCAs (imipramine, amitriptyline).

68

-triptan?

5-HT1B/1D agonists (Sumatriptan).

69

-zepam, -zolam?

Benzodiazepine (diazepam, alprazolam).

70

Drug names - Autonomic - -chol?

Cholinergic agonist (bethanechol, carbachol).

71

-curium, -curonium?

Non depolarizing paralytic (atracurium, vecuronium).

72

-olol?

Beta blocker (propranolol).

73

-stigmine?

AChE inhibitor (neostigmine).

74

-terol?

Beta-2 agonist (albuterol).

75

-zosin?

alpha-1 blocker (prazosin).

76

-afil?

PDE5 inhibitor (sildenafil).

77

-dipine?

Dihydropyridine CCB - Amlodipine.

78

-pril?

ACEIs.

79

-xaban?

Direct factor Xa inhibitors = Apixaban, EDOXABAN, rivaroxaban.

80

Drug reactions - CVS - Coronary vasospasm?

1. Cocaine.
2. Sumatriptan.
3. Ergot alkaloids.

Decks in Pharmacology Class (54):