Fatty acid oxidation Flashcards
What type of fatty acid cannot enter the mitochondria?
Long chain fatty acid
How do medium and short chain fatty acids enter the mitochondria?
How are fatty acids actiated in the mitochondria?
transformed into Acyl-CoAs
Carnitine transport system
Transports acyl-CoAs across the inner mitochondria membrane by turning into acylcarnitine (CPT1) then transferring back to carnitine (CPT2)
What does beta-oxidation produce?
1 Acetyl-CoA, 1 FADH2, 1 NADH, an acyl-CoA reduced by 2 carbons
Makes FADH2 (1st step beta oxidation)
makes NADH (3rd step beta oxidation)
Adds HSCoA to make Acetyl Co-A and acyl-CoA
How many ATP are formed from FADH2?
How many ATP are formed from NADH?
Very long chain acyl-CoA DH prefers how many carbon?
12 to 24
Long-chain acyl CoA DH prefers how many carbons?
12 to 16
Medium chain Acyl-CoA DH prefers how many carbons?
6 to 8
Short chain acyl-CoA DH prefers how many carbons?