Feline Asthma

Question 1

What type of hypersensitivity reaction is feline allergic drug Dz?

Answer 1

Type I

Question 2

What is another name for Type 1 Hypersensitivity reaction?

Answer 2

Allergy

Question 3

What is an allergen?

Answer 3

an antigen that invokes Type I sensitivity

Question 4

What antibody is involved in feline allergic lung Dz? Where is it produced?

Answer 4

IgE

Produced – cells of skin, intestine, and lungs

Question 5

What are the primary immune cells involved in feline asthma?

Answer 5

mast cells
basophils
eosinophils

Question 6

In feline asthma… the type of response the body gives to the antigen is _______, but the magnitude of the response is ___________.

Answer 6

normal

abnormal

Question 7

How is IgE associated with inflammation?

Answer 7

it actives production of inflammatory cells

Question 8

What do the inflammatory cells do to the body in the case of feline asthma?

Answer 8

• inflammatory cells stimulate contraction of smooth muscles around bronchioles to try and stop the inhaled allergen from moving deeper in the airway
• mucous production is stimulated to try and trap the allergen
• inflammatory cells may also congregate around airway and spill into bronchiole or alveolar lumen
• Result = turbulent air flow and decreased air flow thru airways

Question 9

What are common clinical signs of feline asthma?

Answer 9

dyspnea (often episodic)
tachypnea (especially at rest)
wheezing

Question 10

Environmental checklist for feline asthma

Answer 10

• dust free cat litter
• no lids on litter boxes
• don’t use hairspray/perfume around P
• no exposure to smoke (fireplace, cigarette, etc.)
• kept indoors
• clean filters for furnace and vacuum regularly

Question 11

What two types of drugs are used for feline asthma? What do they do to help Tx the clinical signs?

Answer 11

• Bronchodilators increases airway diameter and improves air flow
• Glucocorticoids reduce inflammation

Question 12

What forms are bronchodilators and glucocorticoids found in?

Answer 12

oral tablets

inhalers with face masks