Female Repro III Flashcards Preview

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Flashcards in Female Repro III Deck (23):
1

how much of the surface of the fetal/maternal barrier is just amnion and how much is placenta?

3/4 amnion, 1/4 placenta

2

fetal cells contribute what two layers? maternal layer?

amnion and chorion are fetal (extraembryonic tissues); decidua is maternal

3

properties of the amnion

very thin, cuboidal or columnar epithelium and underlying mesenchyme; high tensile strength

4

is the amnion vascularized?

no

5

chorionic tissues are made up of what type of cell?

trophoblast

6

what is the name of the fetal layer that contacts the placenta? what type of trophoblast cells make it up?

chorion laeve; cytotrophoblasts

7

what are the properties of the chorion laeve?

thin, avascular, mesenchymal layer touches amnion mesenchyme; cytotrophoblastic layer contacts the decidua

8

name four gross functions of the placenta

metabolic, endocrine, exchange and antibodies

9

exchange functions in depth?

uptake of nutrients, removal of waste products, exchange of gases

10

metabolic functions in depth?

cholesterol, amino acids, fatty acids can be produced in the placenta

11

endocrine functions?

synctiotrophoblast can produce estrogen

12

what is the concept of placental function?

to bring the fetus and maternal circulations into close proximity without actually anastomosing

13

placenta statistics

250-500 ml of blood; 2 cm tall, 20 cm long, ovoid, 500g

14

the lobules on the placenta are called

cotelydons

15

what's the name of the connective tissue in which the chorionic vessels run?

chorionic plate

16

what is Wharton's Jelly made of?

hyaluronic acid and chondriotin sulfate

17

what are the three types of villi in the placenta?

stem, terminal and anchoring

18

what mechanisms are used for importation of material into the trophoblast?

passive and facilitated diffusion; active transport and receptor mediated endocytosis

19

what do the cytotrophoblasts do to the spiral artery circulation?

make them impervious to peptides that would constrict the blood vessels (this may lead to hypertension)

20

what enters the trophoblast by diffusion?

gases and vitamins; alcohol/drugs of abuse/therapeutic drugs

21

what enters the trophoblast by transporters?

sugars, amino acids and calcium; drugs of abuse/therapeutic drugs can interfere with transporters

22

what enters the trophoblast by endocytosis?

tranferrin and antibodies; autoantibodies (if present) and RBC antibodies (can be a problem if fetus is different from mother)

23

what's the surface of the synctiotrophoblast covered in?

microvilli that branch - huge surface area