Fentanyl

Question 1

Presentation of Fentanyl

Answer 1

100mcg in 2ml amp

600mcg in 2ml vial

Question 2

Pharmacology of Fentanyl

Answer 2

Synthetic narcotic analgesic

Question 3

Pharmacology of Fentanyl (actions)

Answer 3

CNS effects:

• Depression (leading to analgesia)
• Respiratory depression (leading to apnoea)
• Dependance (addiction)

CV effects:
- Decreases conduction velocity through the A.V. node

Question 4

Metabolsm of Fentanyl

Answer 4

By the liver and excreted by the kidneys

Question 5

Fentanyl Indications

Answer 5

Analgesia
Sedate to facilitate intubation
Sedate to maintain intubation
Drug facilitated intubation

Question 6

Fentanyl Contraindications

Answer 6

Known hypersensitivity

IV Amiodarone

Question 7

Fentanyl Precautions

Answer 7

Oral Amiodarone
Pt's on MAO inhibitors
Respiratory depression, e.g. COPD
Impaired renal/hepatic function
Current asthma
Known addiction to narcotics
Elderly patients
Rhinitis, rhinorrhea or facial trauma (IN)

Question 8

Route of Administraion of Fentanyl

Answer 8

IV

IN

Question 9

Side Effects of Fentanyl

Answer 9

Bradycardia
Apnoea
Respiratory depression
Rigidity of the diaphragm and intercostals

Question 10

Effects of Fentanyl

Answer 10

IV
Onset: immediate
Peak: <5min
Duration: 30-60min

IN
Peak: 2min