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Pharmacology III > FINAL! > Flashcards

Flashcards in FINAL! Deck (9):
1

Smoking cessation

1. Nicotine replacement
2. Buproprion - Zyban
3. Varenicline - Chantix

2

Transdermal patch for smoking

Does not address cravings

10/+ per day - 21 mg/day patch
<10/day - 14 mg/day
Taper dosing over time

3

How to use nicotine gum?

1. Chew until tingly/pepper taste
2. Place btwn cheek & tongue until tingling stops

4

How does buproprion work & who should not use it?

Antagonism of nicotinic acetylcholine recepotors

1. Recent/previous head trauma
2. Severe liver cirrhosis
3. CNS tumors
4. Use of drugs that lower the seizure threshold

5

MOA Chantix

Binds to alpha-4 beta-2 nicotinic receptors
1. Moderate withdrawal Sx
2. Reduced craving
3. Diminished psychological reward

6

CNS stimulants for wt loss?

1. Benzphetamine - Didrex
2. Diethylpropion
3. Methamphetamine - Desoxyn
4. Phendimetrazine - Bontril PDM
5. Phentermine - Adipex-P**

Works 4-6 wks
inc. NE

7

ADRs Belviq

Wt loss supplement
aka Lorcaserin
Careful w/ serotonin syndrome, kidney & liver failure

HA, hypoglycemia in diabetics, back pain, URI inflammation
Cardiac valvular disease?

8

Which wt loss drug makes you shit your brains out?

Xenical

9

SSRI for bulemia?

Fluoxetine