final Flashcards
tidal volume (TV)
the amount of air inspired or expired during a normal quiet breathing cycle
expiratory reserve volume (ERV)
the amount of air that can be expired in addition to the amount normally expired
inspiratory reserve volume (IRV)
the amount of extra air that can be maximally inhaled after a normal inspiration
vital capacity (VC)
the amount of air that can be forcefully expelled after inhaling as much as possible
functional residual capacity (FRC)
defined as the amount of air remaining in the lungs after a normal expiration
RV=?
1L
IRV=
VC-TV-ERV
FRC=
ERV+RV
Hering-breuer reflex
- as the walls of alveoli expand during inhalation,
- stretching of the walls stimulate vagi
- vagi inhibit DRG neurons
high altitude causes what?
- hypoxia
- increased hematocrit
- increased ventilation
high altitude sickness
12000 ft = non life threatening
23000 ft = life threatening
alveoli pressure during inspiration:
air flows into the alveoli because atmospheric pressure is greater than alveolar pressure
alveoli pressure during expiration
air flows out of the alveoli because alveolar pressure is greater than atmospheric pressure
pulmonary pressure during inspiration
- intrapulmonary pressure is less than atmospheric pressure because the volume of the thoracic cavity increases
- at the end of inspiration when the intrapulmonary pressure again equals atmospheric pressure, airflow stops
pulmonary pressure during expiration
intrapulmonary pressure is greater than the atmospheric pressure
apneustic center
provides excitatory activity to DRG, and can prolong inspiration, sets the rhythm for breathing
pneumotaxic center
inhibits the activity of the apneustic center
effects of hyperventilation
- increase breathing
- decrease CO2 & H +
- increase pH
- alkatosis
hypoventilation
- decreases breathing
- increase CO2 & H+
- decreases pH
- acidosis
restricted lungs=
decrease in Total Lung Pressure & Reserve Volume
obstructive lung
decrease in exhalation decrease in FEV
what stimulates RBC production
response to hypoxia
osmotically active particle
cannot cross membrane
Urea 300 Mosmoles w/ 300 mosmoles cell=?
isosmotic, hypertonic
Sucrose 300 Mosmoles w/ 300 mosmoles cell=?
isosmotic, isotonic
300 NaCl Mosmoles w/ 300 mosmoles cell=?
isosmotic, isotonic
150 NaCl Mosmoles w/ 300 mosmoles cell=?
hypoosomotic, hypertonic
600 NaCl Mosmoles w/ 300 mosmoles cell=?
hyposomotic, hypertonic
200 solution w/ 300 cells =
hypo, hypo
400 solution w/ 300 cells =
hyper, hyper
uncontrolled diabetes mellitus
- cannot produce insulin
- more glucose left behind in kidney =
- higher osmotic pressure
- more reabsorption of water in the kidney
- frequent urination
sliding filament model of contraction
excitation contraction ->
release Ca from SR ->
Ca binds to troponin ->
troponin moves tropomyosin off binding site ->
sarcomeres shorten ->
myosin head binding to actin and pulls it ->
Ca pump returns Ca to cisternae
ATP
- breaks actin/ myosin
- myosin splits ATP to ADP (cocks myosin head)
- used in Ca+ pump to return Ca to SR
small motor unit
- few fibers
- weak
- fine motor movement
- small diameter
- slower conduction
- high sensitivity
- early recruitment
- oxidative fibers