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Flashcards in Fluid compartments Deck (14):
1

How is fluid divided in the body?

Total body water=.6(wt); 2/3 ECF, 1/3ICF; of ECF, 3/4 interstitial, 1/4 plasma

2

What is the osmolarity of the three major compartments?

285 mOsm/L

3

What happens in cases of diarrhea?

osmolarity is constant, ecf decreases

4

What happens in Water deprivation?

Osmolarity increases, ecf and icf decrease

5

What happens in adrenal insufficiency?

osmolarity decreases, icf increases and ecf decreases

6

what happens with infusion of isotonic NaCl

osmolarity constant, ecf increases

7

what happens with high NaCl intake

osmolarity increases, icf decreases, ecf increases

8

what happens in SIADH

osmolarity decreases, icf increases more than ecf

9

What are the layers of the glomerular filtration membrane and how much does each do?

endothelial cells-not much; BM-main barrier; epithelial cells (podocytes)- additional barrier

10

what is the basic composition of ultrafiltrate? What gets in?

plasma minus proteins. 42 A-not filtered.

11

sympathetic innervation

L2-L4. Hypogastric nerve. detrusor and trigone muscles

12

parasympathetic innervation

S2-S4. Pelvic nerves->detrusor and trigone. Pudendal->urogenital diaphragm

13

What types of sympathetic receptors are on internal sphincter/detrusor.

detrusor=mostly beta2. internal sphincter=mostly alpha

14

What happens at bladder volume of 300mL? 350? 400?

sensation of fulness. brief micturition contraction but contained---stronger contraction---prolonged contraction, involuntary voiding.