Fungal Infections of the Respiratory Tract I Flashcards Preview

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Flashcards in Fungal Infections of the Respiratory Tract I Deck (30):
1

Zygomycoses

group of uncommon, but potentially fatal infection. infection is rare in normal healthy people

2

How can you identify zygomycoses

non-septate hyphae
sporangia bearing sporangiospores

3

Symptoms of rhinocerebral zygomycosis

nasal congestion, blood tinged rhinorrhea, tender sinuses, headache and fever

4

What can rhinocerebral zygomycosis progress to

facial or periorital edema and visual disturbances, can even get to coma and death

5

How do you treat zygomycoses?

amphotericin B

6

When is candida in yeast form

when it's normal flora

7

When is candida in hyphal form

when it's in tissue

8

Symptoms of oral candidiasis

diffuse erythema and white patches on surface of buccal mucosa, throat, tongue and gums
white lesions

9

How do you treat oral candidiasis

oral formations of nystatin and azole

10

Systemic myocses

diverse group of clinical presentations
not opportunity
acquired by inhibition of fungal elements

11

What do clinical syndromes of systemic mycoeses start as

pulmonary infection

12

What are the systemic mycoses

histoplasma capsulatum
blastomyces dermatititdis
paracoccidiodides brasiliensis
coccidiodies immitis

13

Are systemic mycoses dimorphic?

yes

14

Where is histoplasmosis endemic

mississippi and ohio river valleys

15

What is histoplasmosis associated with

bird and bat droppings

16

How is histoplasmosis transmitted

inhalation

17

What happens in your body when it's infected with histoplasmosis

inhaled sproes are phagocytosed by pulmonary macrophages and convert to yeast form. Yeast replicates within macrophages

18

Symptoms of pulmonary histoplasmosis

mild flu like illness
not a lot of sputum production

19

What is the treatment of pulmonary histoplasmosis

most people don't need intervention

20

Chronic Pulmonary and Disseminated Histoplasmosis symptoms

similiar to TB but with heptomegaly, splenomegaly, and lymphadenopathy

21

How do you treat chronic pulmonary and disseminated histoplasmosis

Amphotericin B

22

How do you treat someone with chronic pulmonary and disseminated histoplasmosis AND AIDS

lifelong suppressive therapy with azoles

23

Blastomycosis

endemic in ohio and missippi river valley
exists in moist soil high in decaying vegetation content

24

How does blastomyces exist in environment

mold

25

How does blastomyces exist in tissue

yeast

26

How can you tell blastomyces from histoplasma in yeast form

blastomyces has a larger size and very thick cell walls

27

symptoms acute blastomycosis

cough, fever, chills, arthralgia, myalgia

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symptoms of chronic pulmonary blastomycosis

cough, fever, night sweats, weight loss, sputum

29

Symptoms of disseminated disease of blastomycosis

skin, bone, and urogenital lesions

30

What is the treatment of blastomycosis

amphotericin B