Fungal Infections of the Respiratory Tract II Flashcards Preview

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Flashcards in Fungal Infections of the Respiratory Tract II Deck (26):
1

Where is paracoccidiomycosis often found

tropical regions of south and central america

2

Is the paracoccidiomycosis more common in men or women

men

3

Disseminated paracoccidiodomycosis presents as what

chronic cutaneous and mucocutaneous ulcers

4

What is the distinctive look of paracoccidiomycosis yeast

mickey mouse years
ship's wheel

5

Where is coccidiodomycosis often found

US - in CA and AZ

6

Structure of coccidiodes immitis

after inhalation it converts to aspherule

7

Symptoms of coccidioidomycosis

mild to moderate flu like symptoms

8

Disseminate coccidiodomycosis

infection of bones, joints, skin, and CNS

9

Coccidial menigitis

develops slowly with increasing headache, fever, stiff neck and other neulogical signs. fatal if untreated

10

How do you treat mild coccidioidomycosis

azole

11

How do you treat disseminated coccidioidomycosis or menegitis

amphotericineB

12

What is the leading form of fungal meningitis

cryptoccus neoformans

13

How can you test for cryptococcus neoformans

india ink stain

14

Is cryptococcus neoformans dimorphic

NO
it's always encapsulated yeast

15

What is cryptococcus neoformans associated with

bird droppings

16

Cryptococcosis pulmonary disease

asymptomatic mild, spontaneously resolvign flu like illnes
little sputum production
little damage to lung

17

Cryptococcosis disseminated disease

skin and bone lesions

18

How do you treat cryptococcosis menigitis

combo of amphotericin B and 5-fluorcytosin or fluconazole

19

Pneumocystis jiroveci (PCP)

highly lethal form of pneumonia
very common in AIDS patients

20

charactersitics of PCP

single celled eukaryotic organism
similiar to protozoa

21

Symptoms of PCP

dyspnea, nonproductive cough, fever, develops weakness, tachypnea, cyanosis and death

22

How do you treat PCP

trimethoprim-sulfamethoxazole

23

Is aspergillosis dimorphic

NO always a mold

24

disseminated aspergillosis infection

invasion of lung parenchyma following infection
fungal hyphae invade lumen and walls of blood vessels, cause thrombosis, infarction and hemorrhage

25

What do aspergillosis hyphae look like

septate with V-shaped branches at 45 degree angle

26

How can you treat aspergillosis

azole, echnocandin, amphotericine B, surgical removal of aspergillomas