dermatophytoses is referred to as what in humans?
* what is it?
“tinea” infections (ringoworm) and named occroding to location
* pathogen of keratinophilic (keratin digesting) soil fungus
1) tinea capitis
2) tinea corporis or ringworm
3) tinea barbae
4) tinea faciei
5) tinea cruiris
6) tinea pedis or athletes foot
7) tinea manuum
8) tinea unguium
1) tinea capitis =CHILDREN; hair and scalp
2) tinea corporis or ringworm =trunk, extremities, face
3) tinea barbae =hair/skin of face; MEN
4) tinea faciei =non-bearded parts of face
5) tinea cruiris or jock itch =groin
6) tinea pedis or athletes foot =foot
7) tinea manuum =hand(s)
8) tinea unguium =nail
what do you use to treat dermatophycosis?
anti-fungal/mycotic agent griseofulvin
* treats infections of skin but you take a pill, do not apply to skin
cell walls of fungi contain?
chitin and B 1:3-linked glucan
fungal infections initiate what type of hypersensitivity?
type 4
where are sterols found?
in cell membrane of fungi; most anti-fungal agents target this component
SEXUAL spores forming examples?
zygospores
ascospores and basidiospores
“BASIcally ASs Sez”
what are asexual spores called?
conidia
* conidium fungi
what means that fungi can form different structures at different temperatures?
dimorphism
* molds at ambient temps and YEAST on host tissue/body temp
fungi are all G- or G+?
G+
Contain DNA or RNA?
both
two forms of fungi?
mold
yeast
are fungal spores resistance to heat like bacteria?
NO
* most completly killed when heated at 80 celcius for 30 min
examples of asexual spores (conidia)?
1) arthrospores -formed by fragmentation of ends of hyphae
2) chlamydospores - thick wall
3) blastospores -formed by budding
4) sporangiospores -formed by sac on a stalk by molds
1) coccidioidomycosis is a disease that infects where first?
2) caused by?
1) first infects the Lungs bc you inhale spores
2) caused by coccidioides
1) blastomycosis caused by?
2) transmitted how?
1) blastomyces dermatitidis
2) initial breath it in, but person to person
1) histpplasmosis caused by?
2) endemic where?
3) causes what infections?
1) histoplasma capslatum
2) in ohio and MI river valleys
3) cause granulomatous, tuberculosis-like infection, pulmonarynodules
what is unique about cryptococcus?
NOT dimorphic
mucormycosis is typically found in?
diabetics or poeple immune suppressed
- NOT dimorphic
- typically fatal
- rhinocerebral infections of sinuses and brain
aflatoxins are produced by?
aspergillus flavus
best known and most intensively researched mycotoxin in the world is?
aflatoxins that are produced by aspergillus flavus
aflatoxins cause damage to?
liver, hepatic carcinoma