Gastric Acid Secretion and its Prevention Flashcards Preview

METABOLISM > Gastric Acid Secretion and its Prevention > Flashcards

Flashcards in Gastric Acid Secretion and its Prevention Deck (10):
1

Name the different contributions to body fluid

saliva, gastric juice, pancreatic juice, bile, intestinal juice

2

What is the function of lysozyme?

destroys bacterial membranes

3

What is the function of growth factors?

stimulate epithelial proliferation which is particularly protective for the oesophageal epithelium which is subject to abrasion

4

Where is mucus secreted in the stomach?

By mucous cells over the entire luminal surface which extend down into glands as mucous neck cells which secrete bicarbonate-rich mucus to coat and lubricate the gastric surface to protect the epithelium

5

Where is acid secreted in the stomach?

by parietal cells (secrete HCl) which activates pepsinogen and inactivates any ingested microorganisms

6

Where are proteases secreted in the stomach?

pepsinogen is secreted by chief cells which is activated by a low pH to pepsin

7

What is the role of lipase?

initiates triglyceride digestion

8

What is the role of intrinsic factor?

glycoproteins from parietal and chief cells bind vitamin B12 in the intestine in order to facilitate absorption

9

What's the most common cause of peptic ulcer?

Helicobacter pylori which is treated with combination of 2 different types of antibiotic and a protein pump inhibitor

10

What's the second most common cause of peptic ulcer?

NSAIDS