Flashcards in Gastrointestinal Physiology Deck (19)
How can long term use of PPIs cause osteoporosis?
Decreased calcium absorption
Long term PPIs can cause hypomagnesaemia, what are symptoms of this?
What infections come from long term PPI use?
What is a treatment for achalasia?
What is gastroparesis?
Muscles of the stomach that cause motility are paralyzed
What happens to stomach emptying time in gastroparesis?
It increases greatly
Pernicious anemia symptoms?
What is highly specific for pernicious anemia?
Serum antibodies for intrinsic factor or parietal cells
What is intrinsic factor needed for?
Absorption of Cobalamin
What is Haptocorrin?
Protects Cobalamin from stomach acid
What encodes for proteins on the surface of cells needed for immune system regulation?
Human leukocyte antigen (HLA)
What is intussusception?
When one section of intestines slides into an adjacent section (telescoping)
What does Hirschsprung's disease affect?
A piece of the colon
What occurs in Hirschsprung's disease?
SM on a section of the colon does not have innervation and thus cannot pass stool
What does a mu-opioid agonist cause?
What binds to mu-opioid receptors?
What does a mu-opioid antagonist cause?
Reversal of constipation
What is a mu-opioid antagonist?