Gastrointestinal Physiology Flashcards Preview

GI Exam 1 > Gastrointestinal Physiology > Flashcards

Flashcards in Gastrointestinal Physiology Deck (19):
1

How can long term use of PPIs cause osteoporosis?

Decreased calcium absorption

2

Long term PPIs can cause hypomagnesaemia, what are symptoms of this?

Seizures
Arrhythmias
Hypotension
Tetany

3

What infections come from long term PPI use?

C. difficile
Community-acquired pneumonia

4

What is a treatment for achalasia?

Botox

5

What is gastroparesis?

Muscles of the stomach that cause motility are paralyzed

6

What happens to stomach emptying time in gastroparesis?

It increases greatly

7

Pernicious anemia symptoms?

Fainting
Chest pain
Angina
Heart attack

8

What is highly specific for pernicious anemia?

Serum antibodies for intrinsic factor or parietal cells

9

What is intrinsic factor needed for?

Absorption of Cobalamin

10

What is Haptocorrin?

Protects Cobalamin from stomach acid

11

What encodes for proteins on the surface of cells needed for immune system regulation?

Human leukocyte antigen (HLA)

12

What is intussusception?

When one section of intestines slides into an adjacent section (telescoping)

13

What does Hirschsprung's disease affect?

A piece of the colon

14

What occurs in Hirschsprung's disease?

SM on a section of the colon does not have innervation and thus cannot pass stool

15

What does a mu-opioid agonist cause?

Constipation

16

What binds to mu-opioid receptors?

Opioids

17

What does a mu-opioid antagonist cause?

Reversal of constipation

18

What is a mu-opioid antagonist?

Alvimopan (Entereg)

19

What is the most common gene associated with celiac disease?

HLA-DQ2