Gene, Protein, Function Flashcards Preview

Zak, MOD 2 > Gene, Protein, Function > Flashcards

Flashcards in Gene, Protein, Function Deck (10):
1

APC

Protein = Adenomatous Polyposis Coli
Function = inhibit WNT

2

NF1

Protein = Neurofibromin-1
Function = inhibit RAS/MAPK

3

NF2

Protein = Merlin
Function = cytoskeletal stability

4

PTCH

Protein = Patched
Function = inhibit Hedgehog

5

RB

Protein = RB
Function = inhibit G1/S transition

6

VHL

Protein = VHL
Function = inhibit HIF-1a

7

CDH1

Protein = E-cadherin
Function = cell adhesion, inhibit cell motility

8

BRCA1/2

Protein = Breast cancer 1/2
Function = repair dsDNA breaks

9

MSH

Protein = MSH1/6
Function = DNA mismatch repair

10

WT1

Protein = Wilms tumor 1
Function = transcription factor