Gene Structure and Function I & II Flashcards Preview

Genetics (David Oh) > Gene Structure and Function I & II > Flashcards

Flashcards in Gene Structure and Function I & II Deck (17):
1

what guides RNA polymerase where to start

TATA

2

what are some regulatory elements

enhancer or sliencer

3

HDAC

histone deacylase. take acetylation off.

4

what is used to transcribe protein coding genes

RNA polymerase II

5

what side is transcriptional modulation on?

N terminus

6

what side is ligand binding on?

C terminus

7

what is the exact structure of the polyadenylation?

AAUAAA

8

TF and how many % of genes?

transcription factors, 8

9

what type of therapy for prostate cancer?

androgen antagonists

10

SERM

selective estrogen receptor modulators

11

what type of RNA is most common in mamm cell

rRNA

12

what is miRNA made from and what does it get chopped by

dsRNA, Dicer

13

what does telomerase add?

TTAGGG at 3' end

14

is RNA destroyed in translational silencing?

no

15

trimethyl cap

added to 5' following transcription

16

what are the flanking nucleotides

GU... ...AG ps. C/U-rich

17

polyadenylation signal

AAUAAA added 3' of mRNA