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CV PATH...Peripheral Arterial Disease > General > Flashcards

Flashcards in General Deck (15)
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1

usually refers to

chronic atherosclerotic occlusive disease of large and medium arteries, primarily of the legs

2

epidemiology

common
elderly
men
risk factors same as for CAD

3

Atherosclerotic luminal narrowing decreases blood flow...

in inverse proportion to length of stenosis and blood viscosity

in proportion to radius to the fourth power

**Poiseuille's eqn.

4

What is important in determining the amount of blood flow?

radius of the lumen

5

if radius is reduced to half, flow is....

reduced to 1/16

6

Symptoms

intermittent claudication

7

intermittent claudication

pain brought on by exercise, relieved by rest

8

Where is the pain most common?

calf muscles when disease in femoral or popliteal arteries (the usual site) causes it

9

What are indicators of severe disease?

pain at rest
ulcers

10

Signs

diminished or lost distal pulses
brits
pallor or cyanosis
skin atrophy muscle atrophy
ulcerations
necrosis (gangrene)

11

bruits

swishing sounds auscultated over lesions with turbulent flow

12

Diagnosis

made by Hx and physical exam!!!

13

Physical exam useful for diagnosis

measure BP in arm and lower leg w/ pt supine...
if ratio ("ankle/brachial ratio") is <.9, no further diagnostic tests are necessary

14

First line treatment

exercise (esp walking)
--helps develop collaterals

cilostazol (vasodilates)
penoxifylline (decreases blood viscosity)
angioplasty
surgery (bypass, amputation)

15

claudication

ischemic pain of periphery, usually legs, usually calves, usually intermittent, usually brought on by exertion and relieved by rest