Flashcards in general immunology Deck (17):
what is an allergy
an inappropriate/harmful immune response to foreign substances which is normally harmless
what is an allergen
proteins that elicit an IgE response in allergic individuals
what is a RAST test?
blood test that measures IgE levels to a specific allergen
what causes the early response of allergies?
advantages and disadvantages to Skin prick Test
fast, sensitive, cheap; risk of anaphylaxis, not specific
gold standard of allergy diagnosis?
main causes of fatal anaphylaxis
drugs, insect venom, food allergy
moderated and severe symptoms of anaphylaxis?
angioedema, hypotension, wheeze, LOC
the dose of adrenaline in epipen for adult
first line treatment for hay fever
nasal corticosteroid then antihistamine
some medication options for allergic rhinitis?
Adjunct nasal corticosteroids
Nasal sodium cromoglycate
Immunotherapy- with consultation by allergy specialist
what are some ix we can do for allergies?
1. skin prick test
2. serological testing= RAST
3. challenge test
what is a contraindication to immunotherapy?
who gets subcutaneous immunotherapy?
patients with allergies to bee stings, allergic rhinitis or sometimes allergic asthma
risk factors for fatal anaphylaxis?
lack of epipen
what enzyme do we measure for anaphylaxis
mast cell tryptase