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Flashcards in general immunology Deck (17):
1

what is an allergy

an inappropriate/harmful immune response to foreign substances which is normally harmless

2

what is an allergen

proteins that elicit an IgE response in allergic individuals

3

what is a RAST test?

blood test that measures IgE levels to a specific allergen

4

what causes the early response of allergies?

histamine release

5

advantages and disadvantages to Skin prick Test

fast, sensitive, cheap; risk of anaphylaxis, not specific

6

gold standard of allergy diagnosis?

challenge test

7

main causes of fatal anaphylaxis

drugs, insect venom, food allergy

8

moderated and severe symptoms of anaphylaxis?

angioedema, hypotension, wheeze, LOC

9

the dose of adrenaline in epipen for adult

0.5mg

10

first line treatment for hay fever

nasal corticosteroid then antihistamine

11

some medication options for allergic rhinitis?

Oral antihistamines
Nasal antihistamines
Adjunct nasal corticosteroids
Nasal sodium cromoglycate
Immunotherapy- with consultation by allergy specialist

12

what are some ix we can do for allergies?

1. skin prick test
2. serological testing= RAST
3. challenge test

13

what is a contraindication to immunotherapy?

beta blockade

14

who gets subcutaneous immunotherapy?

patients with allergies to bee stings, allergic rhinitis or sometimes allergic asthma

15

risk factors for fatal anaphylaxis?

lack of epipen
adolescence
alcohol

16

what enzyme do we measure for anaphylaxis

mast cell tryptase

17

describe angiooedema

deep tissue swelling
often seen in anaphylaxis
associated with burning sensation