GI - 8 Antibiotic Associated Diarrhea and C. Diff Flashcards Preview

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Flashcards in GI - 8 Antibiotic Associated Diarrhea and C. Diff Deck (15)
1

Is antibiotic-associated diarrhea common?

Hells yes

2

What resolves antibiotic associated diarrhea?

Discontinuation of antibiotic

3

What's the most common cause of antibiotic-associated diarrhea?

changes in colonic bacterial fermentation of carbohydrates (C diff causes fewer cases)

4

What's the cause of Antibiotic-associated colitis?

C diff

5

How does Antibiotic-associated colitis happen?

Antibiotics knock out good flora as well as bad flora. Then a hospital patient/staff passes C. Diff to them and they get this.

6

Drug to treat antibiotic associated colitis

Clindamycin

7

2 examples of fluoroquinolones:

Ciprofloxicin, levofloxicin

8

Mild-mod greenish, foul smelling watery diarrhea
Lower abdominal cramps when going to the bathroom
Normal or mild left lower quadrant tenderness

C diff diarrhea

9

The key 2 symptoms of C Diff colitis are:

Watery diarrhea
with mucous and lots of blood

10

What's a test to diagnose C diff? How does it work?

PCR - tests for toxin B (one of A&B toxins made by C diff)

11

Yellow adherent plaques over colonic mucosa is a sign of:

Pseudomembranous colitis

12

What imaging test is done for patients with severe symptomatology when rapid diagnosis needed?

Sigmoidoscopy

13

Drug for treating Pseudomembranous colitis

Metronidazole

14

What's the difference between Antibiotic-associated colitis and antibiotic associated pseudomembranous colitis?

Pseudomembranous colitis is a very severse case of antibiotic-associated colitis. It has yellow adherent plaques as well

15

Drug for relapses of antibiotc pseudomembranous colitis

**Most relapses respond promptly to a 2nd course of metronidazole therapy.