Flashcards in GI - ANDERSON Deck (26):
What cells secrete Histamine in the ST?
what triggers this?
Gastrin from G cells trigger ECL-cells to release Histamine which stimulates the Proton Pump and release of Gastric H+
What are the cells of the Duodenum and Jejunum that secrete and aid in digestion?
K --> GIP -> stimulate beta cells to release insulin
I -> CCK -> release of bile
S -> secretin -> stim. pancrease and GB to release BICARB
K cells of the SI release?
I cells of the SI release?
What is absorbed in the terminal ileum?
What about Iron?
bile salts and B12
- iron is absorbed in the duodenum
Primary Bile Acids
Secondary Bile Acids are converted from primary via what?
bacteria in the SI
Conjugation of bile acids makes BILE SALTS which is done by the _____ with AA's _____ and ______.
- GLYCINE, TAURINE
RLE enzyme of bile acid synthesis?
B3, NAC, is used in what kinds of rxns?
Xu is called?
Xu --> Pellagra
Remember, B5 is ...
- pantothenic acid
Active form of B6 is...
- AA metabolism
- needs Mg as cofactor
Homocysteine -> Methionine
B12 - COBALAMIN
B12 also frees _____ to make THF.
Vit C used in what type of RXNs?
Biotin used in what type of RXNs?
- if you eat too much raw egg, you will not absorb biotin
A stored mainly in LR as?
E stored mainly in ?
Various forms of Vit D:
SKIN - D3 or Cholecalciferol
LR - 25 hydro D3
KD - 1-25-dihydro D3
D3 is made from what with the help of UV light?
25 hydro D3 can make two forms of D in the KD depending on Ca levels and PTH.
+PTH ---> 1-25 dihydro D3 (increase serum Ca)
-PTH ---> 24-25 dihydro D3 (decreases serum Ca)
Selenium is part of?
- mercury poisoning - heavy metals
Cobalt is part of vitamin?
B12 hence COBAlamin
CoQ10 is located where?
- made w cholesterol
- also an antioxidant
- made in the cholesterol pathway
Glutathione is a tripeptide made of?
Step 1: Glutamate + Cysteine
.... Cysteine is rate limiting component
.... w enzyme GGCS
Step2: Glycine added w GSH enz (glutathione synthetase)